Table 2 Significantly enriched KEGG pathways ( P < 0.05) using proteins with higher expression levels in IC areas
Pathway name | Count | Differentially expressed proteins | P-value |
|---|---|---|---|
Focal adhesion | 14 | ACTG1,ACTN1,COL1A2,COL6A1,COL6A2,FLNA,ITGA1,LAMA4,LAMC1,MYLK,MYL9,COL6A3,TLN1,VCL | 7.1E-8 |
ECM-receptor interaction | 8 | COL1A2,COL6A1,COL6A2,HSPG2,ITGA1,LAMA4,,LAMC1,COL6A3 | 1.8E-5 |
Regulation of actin cytoskeleton | 8 | ACTG1,ACTN1,GSN,ITGA1,MYLK,MYL9,PIP4K2C,VCL | 5.2E-3 |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 4 | ACTG1,ACTN1,DES,ITGA1 | 3.7E-2 |
Leukocyte transendothelial migration | 5 | ACTG1,ACTN1,MLT4,MYL9,VCL | 3.7E-2 |
Adherens junction | 4 | ACTG1,ACTN1,MLT4,VCL | 4.0E-2 |
Tight junction | 5 | ACTG1,ACTN1,MLT4,MYH11,MYL9 | 4.9E-2 |