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Table 1 Recommendations for the conduct of animal studies to evaluate GE crops[101]

From: GMOs in animal agriculture: time to consider both costs and benefits in regulatory evaluations

Animals (species/categories) Number of animals (coefficient of variation 4 to 5%) Duration of experiments Composition of diets Measurements/endpoints
Poultry for meat production 10-12 pens per treatment with 9–12 birds per pen 5 wk or more Balanced diets Feed intake, gain, feed conversion, metabolic parameters, body composition
Poultry for egg production 12-15 replications per treatment with 3–5 layers per pen 18-40 wk of age, at least three 28-d phases Balanced diets Feed intake, egg production, feed conversion, egg quality
Swine 6-9 replications per treatment with 4 or more pigs per replication Piglets (7–12 kg) 4–6 wk Growers (15–25 kg) 6–8 wk Balanced diets Feed intake, gain, feed conversion, metabolic parameters, carcass quality
Growing and finishing ruminants 6-10 replications per treatment with 6 or more cattle per replication 90-120 d Balanced diets Feed intake, grain, feed conversion, carcass data, metabolic parameters
Lactating dairy cows 12-16 cows per treatment 28 cows per treatment Latin square 28 d periods Randomized block design Balanced diets Feed intake, milk performance and composition, body weight, body condition score (BCS), cell counts in milk, animal health
  1. Table used with permission[2].