Fig. 7

The overexpression of Sirt3 may alleviate BHBA-induced injury by enhancing autophagy by the regulation of the AMPK-mTOR pathway. The p-AMPK (A–B), p-mTOR (C–D), and the relative expression of Beclin-1 (E–F) in different groups as detected by western blotting (n = 3). For the left of Fig. 7B, D and F, we used Student t-tests for significant difference analysis (^*P < 0.05; ^**P < 0.01); for the right of Fig. 7B, D and F, we used one-way ANOVA for significant difference analysis (the different lowercases represent P < 0.05)