Table 3 Functional enrichment analysis for the input list of the collected candidate genes
From: Candidate genes for mastitis resistance in dairy cattle: a data integration approach
GO:BP | GO:MF | GO:CC | ||||||
|---|---|---|---|---|---|---|---|---|
Term name | Term ID | P adj | Term name | Term ID | P adj | Term name | Term ID | P adj |
Response to stress | GO:0006950 | 2.229 × 10−48 | Chemokine activity | GO:0008009 | 2.078 × 10−13 | Extracellular region | GO:0005576 | 8.251 × 10−18 |
Defense response | GO:0006952 | 1.292 × 10−46 | Signaling receptor binding | GO:0005102 | 4.433 × 10−12 | Extracellular space | GO:0005615 | 5.248 × 10−16 |
Immune system process | GO:0002376 | 5.366 × 10− 43 | Protein binding | GO:0005515 | 7.952 × 10−12 | Cytoplasm | GO:0005737 | 3.469 × 10−15 |
Response to external stimulus | GO:0009605 | 1.122 × 10−37 | Chemokine receptor binding | GO:0042379 | 3.461 × 10−11 | Plasma membrane protein complex | GO:0098797 | 1.408 × 10−10 |
Immune response | GO:0006955 | 2.454 × 10−37 | Cytokine activity | GO:0005125 | 3.795 × 10−11 | Cell surface | GO:0009986 | 6.243 × 10−10 |
Response to organic substance | GO:0010033 | 3.460 × 10−33 | ABC-type transporter activity | GO:0140359 | 8.961 × 10−11 | External side of plasma membrane | GO:0009897 | 2.348 × 10−9 |
Inflammatory response | GO:0006954 | 1.027 × 10−32 | Immune receptor activity | GO:0140375 | 1.822 × 10−10 | Cell periphery | GO:0071944 | 2.209 × 10−8 |
Response to biotic stimulus | GO:0009607 | 1.247 × 10−32 | Cytokine receptor activity | GO:0004896 | 9.780 × 10−10 | Endomembrane system | GO:0012505 | 7.691 × 10−8 |
Response to other organism | GO:0051707 | 2.191 × 10−32 | Cytokine receptor binding | GO:0005126 | 3.058 × 10−9 | Extracellular matrix | GO:0031012 | 8.426 × 10−8 |
Regulation of immune system process | GO:0002682 | 3.557 × 10−32 | Enzyme binding | GO:0019899 | 5.853 × 10−9 | External encapsulating structure | GO:0030312 | 9.481 × 10−8 |