Fig. 6

Taurine supplement increases the taurine levels in serum and uteri, and partly rescues the defects of embryo implantation in the CDO KO mice. A, Serum taurine concentration. B, Taurine concentration in uterus tissues. C, Representative images of implantation sites. Bars: 1 cm. WT: wide type female mice. KO: Cdo KO female mice. KO + taurine: Cdo KO female mice supplied with taurine. n = 3 for each genotype. D, Blastocysts flushed out from Cdo KO uterus. Bar, 50 μm. E, Numbers of implantation sites. Data are presented as Mean ± SEM. Different letters represent significant differences (P < 0.05, n ≥ 3)