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Table 4 Blood-milk-barrier integrity indices in serum and milk of dairy cows with low- and high-DSCC at week – 1 or + 1 relative to calving1

From: Blood neutrophil extracellular traps: a novel target for the assessment of mammary health in transition dairy cows

Items

– 1 Wk2

 + 1 Wk2

 

P-value3

Low DSCC

High DSCC

Low DSCC

High DSCC

SEM

Hs

Wk

Hs × Wk

In serum

 Lactose, μmol/L

3.51b

3.29b

7.59a

6.69a

0.389

0.39

 < 0.01

0.57

 α-lactalbumin, μg/mL

0.83b

0.94ab

1.03a

1.09a

0.038

0.28

0.01

0.69

 β-casein, μg/mL

4.72b

5.33a

5.12ab

5.53a

0.108

0.05

0.04

0.48

In milk

 Na+/K+ ratio

-

-

0.250

0.253

0.0098

0.87

-

-

 Bovine serum albumin, mg/mL

-

-

0.689

0.717

0.0185

0.46

-

-

 Immunoglobulin G1, μg/mL

-

-

36.3

37.5

0.85

0.48

-

-

 Immunoglobulin G2, μg/mL

-

-

25.2

28.3

0.94

0.09

-

-

  1. 1The data are expressed as the mean ± SEM, n = 15. a,b,cP < 0.05
  2. 2DSCC Differential somatic cell count, – 1 Wk Week – 1 relative to calving, + 1 Wk Week + 1 relative to calving
  3. 3Hs Health status, Wk Sampling week, Hs × Wk Interaction between health status and sampling week