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Table 7 Effect of dietary Enterococcus faecium NCIMB 11181 supplementation on mRNA abundance of tight junction in the ileum of broiler chickens challenged with Salmonella Typhimurium

From: Pretreatment with probiotics Enterococcus faecium NCIMB 11181 attenuated Salmonella Typhimurium-induced gut injury through modulating intestinal microbiome and immune responses with barrier function in broiler chickens

Items

ST1

MLCK

Claudin-1

Occludin

ZO-1

ZO-2

Dosage, mg/kg

  0

–

1.03

1.05

1.06

1.02

1.01

  200

–

0.85

0.86

0.74

0.98

1.04

  0

 + 

1.61

0.48

0.47

0.69

0.68

  200

 + 

2.03

0.58

0.59

0.74

0.66

  SEM2

 

0.153

0.070

0.074

0.052

0.054

Main factors

  0

 

1.30

0.79

0.79

0.87

0.86

  200

 

1.44

0.73

0.68

0.86

0.85

  Non-challenged

 

0.94b

0.95a

0.90a

1.00a

1.02a

  Challenged

 

1.84a

0.53b

0.52b

0.72b

0.67b

Main factors and Interaction (P -value)3

  Enterococcus faecium

 

0.638

0.682

0.419

0.981

0.971

  Challenged

 

0.002

0.001

0.007

0.005

0.000

  Enterococcus faecium × Challenged

 

0.233

0.197

0.082

0.660

0.763

  1. 1Challenged with Salmonella Typhimurium, –, without ST challenged, + , with ST challenged
  2. 2SEM, standard error of the mean
  3. 3P-value represent the main effect of the diet, the main effect of ST challenged, and the interaction between the dietary treatments and ST challenged
  4. a,bMeans in the same column without common superscripts differ significantly (P < 0.05)