Stimbiotic supplementation modulated intestinal inflammatory response and improved broilers performance in an experimentally-induced necrotic enteritis infection model

Table 2 Effects of vaccine overdose and C.perfringens infection on growth performance in broiler chickens (Exp. 1)¹

Clostridium perfringens (C)	Vaccine (V)	BW		BWG	FI	FCR
Clostridium perfringens (C)	Vaccine (V)	14 d	24 d	BWG	FI	FCR
No	0	381	910	530	940	1.78
No	× 10	378	891	511	909	1.78
No	× 20	382	898	518	914	1.77
Yes	0	375	897	518	907	1.75
Yes	× 10	383	866	487	870	1.79
Yes	× 20	379	866	487	855	1.74
SEM²		3.5	9.0	10.3	8.5	0.02
Clostridium Perfringens
No		380	899^a	520^a	921^a	1.78
Yes		379	877^b	497^b	877^b	1.76
	Vaccine
	0	378	903^a	524^a	923^a	1.77
	× 10	380	878^b	498^b	890^b	1.79
	× 20	381	882^b	502^b	88^b	1.76
P-value
C		0.95	0.003	0.003	< 0.001	0.66
V		0.98	0.01	0.01	0.001	0.80
C × V		0.99	0.58	0.58	0.39	0.11

Mortality was not observed in this experiment
n = 20 birds/treatment. All birds received allotted treatment diet starting study 0 d
¹0, non-vaccine challenge; × 10, oral administration the levels of × 10 recommended dose of vaccine; × 20, oral administration the levels of × 20 recommended dose of vaccines; No, non-oral challenged with CP; Yes, oral challenged with 3 mL of 2.2 × 10⁷ CFU CP; BW body weight, BWG body weight gain, FI feed intake, FCR feed conversion ratio
²SEM standard error of mean
^a,bMeans in the same column with different superscripts are significantly different by Student’s test (P < 0.05)

ISSN: 2049-1891