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Table 5 List of overlapping genes between weighted single-step genome-wide association analysis and RNA sequencing

From: Weighted single-step GWAS and RNA sequencing reveals key candidate genes associated with physiological indicators of heat stress in Holstein cattle

Trait

Gene symbol

Log2 Ratio

FDR

(Non-heat stress/ Heat stress)

Rectal temperature

PMAIP1

1.21

1.11E-02

Rectal temperature

SBK1

1.73

1.41E-03

Rectal temperature

TMEM33

−1.35

4.35E-03

Rectal temperature

TUT7

−1.39

5.92E-03

Rectal temperature

NAA35

−1.09

3.47E-05

Respiration rate score

GATB

−1.36

2.44E-05

Respiration rate score

CHORDC1

−1.64

1.99E-10

Respiration rate score

TIPRL

−1.36

1.91E-04

Respiration rate score

DCAF6

−1.01

1.97E-04

Respiration rate score

RTN4IP1

−1.14

4.96E-05

Respiration rate score

CRYBG1

−1.14

6.40E-06

Drooling score

BTBD7

−1.02

1.19E-03

Drooling score

DNTTIP2

−1.37

1.48E-09

Drooling score

NCAPG

−1.53

7.59E-05