Gestational heat stress alters skeletal muscle gene expression profiles and vascularity in fetal pigs in a sexually dimorphic manner

Table 4 KEGG pathways significantly enriched (false discovery rate (FDR) ≤ 0.05) by the ranked gene list for the comparison of heat stress (HS) vs. control (CON) in female fetal longissimus dorsi (LD) muscles at fetal d 60 age

KEGG pathway	False discovery rate	NES
JAK/STAT signaling pathway	0.005	− 1.90
Adherens junction	0.013	−1.80
DNA replication	0.018	1.84
Epithelial cell signaling in Helicobacter pylori infection	0.026	−1.81

NES Normalised enrichment score. A positive NES, the pathway was mostly enriched by upregulated genes (HS compared to CON). A negative NES, the pathway was mostly enriched by the downregulated genes (HS compared to CON)

ISSN: 2049-1891