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Table 2 Male fertility prediction value of single markers

From: Establishment of a male fertility prediction model with sperm RNA markers in pigs as a translational animal model

Gene

Cut-off value

AUC

Sensitivity, %

Specificity, %

NPV, %

PPV, %

OA, %

EQTN

1.0

0.8

70.0

70.0

70.0

70.0

70.0

ZP4

1.2

0.9

90.0

90.0

90.0

90.0

90.0

UNC13B

1.5

0.6

60.0

50.0

55.6

54.5

55.0

RIMS1

1.1

0.6

50.0

40.0

44.4

45.5

45.0

SPACA3

2.0

0.8

70.0

70.0

70.0

70.0

70.0

  1. AUC Area under the curve. Sensitivity is the percentage of pigs showing true-positive results when tested with mRNA expression. Specificity is the percentage of pigs showing true-negative results. The positive predictive value (PPV) is the percentage of pigs that tested as positive and simultaneously showed true-positive litter size. The negative predictive value (NPV) is the percentage of pigs that tested as negative and simultaneously showed true-negative litter size. OA overall accuracy