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Fig. 7 | Journal of Animal Science and Biotechnology

Fig. 7

From: Tauroursodeoxycholic acid (TUDCA) improves intestinal barrier function associated with TGR5-MLCK pathway and the alteration of serum metabolites and gut bacteria in weaned piglets

Fig. 7

TUDCA improved E. coli-induced epithelial barrier impairment and enhanced TGR5 expression in IPEC-J2 cells. A Western blot analysis of ZO-1, OCC, Claudin-1, FXR and TGR5 in IPEC-J2 cells. Tubulin was used as the loading control. B Mean ± SEM of immunoblotting bands of ZO-1, OCC, Claudin-1, FXR and TGR5 (n = 4). C LDH activity in the supernatant of IPEC-J2 cells, expressed as fold of control. *P < 0.05 and ***P < 0.001 versus the control (CON) group, #P < 0.05 and ##P < 0.01versus the E. coli group

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Journal of Animal Science and Biotechnology

ISSN: 2049-1891