Impacts of weaning weights and mycotoxin challenges on jejunal mucosa-associated microbiota, intestinal and systemic health, and growth performance of nursery pigs

Table 6 Serum variables observed in pigs at 20 kg with different weaning weights and mycotoxin challenges

Weaning weight (WW)	< 7.5 kg		> 9.0 kg		SEM	P-value
Mycotoxin¹ (MTX)	–	+	–	+	SEM	WW	MTX	WW × MTX
Liver health
Total protein, g/dL	5.05	5.08	5.07	4.88	0.15	0.496	0.576	0.422
Albumin, g/dL	3.28	2.95	3.07	2.93	0.14	0.311	0.051	0.383
Globulin, g/dL	1.77^b	2.13^a	2.00^ab	1.95^ab	0.12	0.833	0.192	0.091
Albumin/Globulin	1.88	1.43	1.57	1.52	0.12	0.340	0.050	0.110
AST, IU/L	34.8	32.2	35.2	41.2	5.3	0.386	0.755	0.420
ALT, IU/L	19.3	17.5	19.7	18.7	1.4	0.587	0.310	0.762
AST/ALT	1.80	1.90	1.81	2.16	0.25	0.587	0.370	0.616
ALP, IU/L	277	263	204	241	23	0.049	0.635	0.275
CPK, IU/L	884	884	849	910	244	0.985	0.901	0.903
Cholesterol, mg/dL	81.5	82.0	76.2	74.0	5.6	0.194	0.868	0.791
BUN, mg/dL	12.0	11.7	12.7	10.7	0.9	0.861	0.230	0.386
Creatinine, mg/dL	0.63^b	0.58^b	0.65^abY	0.72^aX	0.03	0.011	0.758	0.041
BUN/Creatinine	19.0^a	20.2^a	19.3^a	14.8^b	1.4	0.085	0.240	0.053
Glucose, mg/dL	113	111	109	102	5	0.166	0.410	0.653
Electrolytes
Phosphorus, mg/dL	9.17^ab	9.78^a	9.78^a	8.67^b	0.34	0.470	0.470	0.019
Calcium, mg/dL	10.8	10.8	10.7	10.5	0.2	0.339	0.705	0.644
Sodium, mEq/L	145	145	145	145	1	0.445	0.445	0.645
Potassium, mEq/L	5.52	5.45	5.77	5.48	0.28	0.466	0.369	0.576
Na/K	26.3	26.8	25.2	26.8	1.3	0.528	0.247	0.528
Chloride, mEq/L	102	102	105	105	1	0.007	0.911	0.911

¹Dietary treatments were based on 2 phases: phase 1 from d 0 until animals achieved 11 kg of body weight (4 d for pig weaning weight > 9 kg and 14 d for pig weaning weight < 7.5 kg) and phase 2 until pigs achieved 20 kg of body weight (17 d for both weaning weight groups). AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; BUN, blood urea nitrogen; CPK, creatine phosphokinase. ^{a, b} Means within a row with a different superscript differ (P < 0.05). ^{X, Y} Means within a row with a different superscript tend to differ (0.05 ≤ P < 0.10)

ISSN: 2049-1891