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Table 4 Circadian rhythm parameters of all clock genes in hypothalamus, as determined by cosinor analyses

From: Chronic corticosterone disrupts the circadian rhythm of CRH expression and m6A RNA methylation in the chicken hypothalamus

Index

Group

CLOCK

BMAL1

CRY1

CRY2

PER2

PER3

Mesor

CON

1.13 ± 0.05

1.11 ± 0.04

1.13 ± 0.05

0.90 ± 0.02

0.52 ± 0.06

0.63 ± 0.07

CORT

ND

0.84 ± 0.06*

ND

ND

0.34 ± 0.02*

ND

Amplitude

CON

0.45 ± 0.07

0.44 ± 0.06

0.58 ± 0.07

0.17 ± 0.03

0.36 ± 0.08

0.55 ± 0.09

CORT

ND

0.15 ± 0.09*

ND

ND

0.19 ± 0.03*

ND

Acrophase, h

CON

8.94 ± 0.53

8.43 ± 0.48

8.53 ± 0.43

6.21 ± 0.72

2.53 ± 0.92

22.88 ± 0.64

CORT

ND

7.51 ± 2.01

ND

ND

2.03 ± 0.63

ND

  1. Values are means ± SEM. *P < 0.05, **P < 0.01, compared with CON group. ND represents not determined as there was no circadian rhythm