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Table 3 Circadian rhythm parameters of all clock genes in hippocampus, as determined by cosinor analyses

From: Chronic corticosterone disrupts the circadian rhythm of CRH expression and m6A RNA methylation in the chicken hypothalamus

Index

Group

CLOCK

BMAL1

CRY1

CRY2

PER2

PER3

Mesor

CON

1.15 ± 0.03

1.50 ± 0.09

1.36 ± 0.18

0.99 ± 0.08

0.49 ± 0.05

0.54 ± 0.04

CORT

1.05 ± 0.06

1.60 ± 0.08

1.26 ± 0.06

1.05 ± 0.05

0.44 ± 0.05

0.58 ± 0.06

Amplitude

CON

0.27 ± 0.04

0.58 ± 0.12

0.86 ± 0.27

ND

0.44 ± 0.07

0.45 ± 0.06

CORT

0.23 ± 0.08

0.65 ± 0.12

0.45 ± 0.27

0.09 ± 0.12

0.27 ± 0.02*

0.41 ± 0.08

Acrophase, h

CON

10.64 ± 0.55

11.14 ± 0.79

8.53 ± 0.28

5.89 ± 1.87

3.27 ± 0.69

23.80 ± 0.56

CORT

11.51 ± 1.35

11.43 ± 0.69

10.51 ± 0.70*

ND

3.37 ± 0.32

23.13 ± 0.78

  1. Values are means ± SEM. *P < 0.05, **P < 0.01, compared with CON group. ND represents not determined as there was no circadian rhythm