Fig. 9From: Natural astaxanthin enhanced antioxidant capacity and improved semen quality through the MAPK/Nrf2 pathway in aging layer breeder roostersSchematic diagram summarizing the mechanisms by which natural astaxanthin (ASTA) promotes the antioxidant defense system in aging roosters. The antioxidant defense system is down regulated in the natural aging process in roosters. ASTA attenuated the oxidative stress in the testes via the activation of the mitogen-activated protein kinase/nuclear factor-erythroid 2-related factor 2 (MAPK/Nrf2) pathway to attenuate the age-related sub-fertility in aging layer breeder roosters. ARE, antioxidant responsive element; CAT, catalase; GSH-Px, glutathione peroxidase; ERK, extracellular signal-related kinase; JNK, c-Jun N-terminal kinase; SOD, superoxide dismutaseBack to article page