Items | Ctrl | PF | HS | HS + 25-OH-D3 |
---|---|---|---|---|
Gait score | 2.10 ± 0.28 | 1.38 ± 0.11 | 1.93 ± 0.23 | 1.37 ± 0.12* |
Bone growth | ||||
 Length, mm | 104.96 ± 1.80 | 103.26 ± 1.47 | 105.30 ± 1.11 | 105.31 ± 1.07 |
 Width, mm | 9.70 ± 0.23 | 9.96 ± 0.20 | 9.39 ± 0.21 | 9.50 ± 0.25 |
 Fat-free weight, g | 7.53 ± 0.25 | 7.51 ± 0.16 | 7.29 ± 0.18 | 7.29 ± 0.15 |
Bone mineralization | ||||
 Ash, %Fat-free weight | 45.71 ± 0.26a | 46.08 ± 0.41a | 43.91 ± 0.59b | 45.92 ± 0.42* |
 Density, g/mL | 0.45 ± 0.01 | 0.44 ± 0.01 | 0.42 ± 0.01 | 0.45 ± 0.01* |
 Cortical thickness in diaphysis, μm | 25.18 ± 1.80 | 26.06 ± 2.39 | 24.32 ± 0.96 | 28.25 ± 1.65* |
 BV/TV in diaphysis, % | 0.56 ± 0.01 | 0.55 ± 0.01 | 0.54 ± 0.01 | 0.55 ± 0.01 |
 Trabecular thickness in metaphysis, μm | 4.14 ± 0.05 | 4.17 ± 0.09 | 4.19 ± 0.05 | 4.32 ± 0.03* |
 BV/TV in metaphysis, % | 0.25 ± 0.01 | 0.27 ± 0.03 | 0.24 ± 0.01 | 0.25 ± 0.01 |
Bone mechanical properties | ||||
 Fracture load, N | 708.33 ± 23.86a | 725 ± 28.14a | 587.5 ± 33.74b | 707.14 ± 33.5* |
 Yield load, N | 710.65 ± 77.63 | 678.56 ± 42.13 | 594.27 ± 51.06 | 769.00 ± 69.67 |
 Slope, N/mm | 310.91 ± 62.24 | 324.98 ± 82.38 | 296.30 ± 24.34 | 472.13 ± 50.13* |
 AUC, N × mm × 103 | 3.36 ± 0.36 | 3.14 ± 0.39 | 2.63 ± 0.21 | 3.15 ± 0.34 |