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Table 1 List of significantly altered metabolites in the intestine of piglets between CON and LPS groups

From: L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide

Metabolite

Similarity

R.T.

Mass

VIP

P value

FC

1-Mono-olein

727.11

22.65

399

1.80

0.0394

2.52

1-Deoxyerythritol

764.13

8.13

91

1.70

0.0088

0.21

3,4-Dihydroxyphenylacetic acid

876.07

15.47

147

1.55

0.0454

2.74

Dihydrocholesterol

914.89

6.33

130

1.62

0.0154

0.20

Erythritol

811.63

6.39

241

1.65

0.0338

5.34

Erythronic acid

616.93

16.51

174

1.80

0.0296

0.30

Glutaric acid

731.94

10.85

174

1.51

0.0129

0.42

Isoleucine minor

911.98

18.16

95

1.92

0.0253

1.98

Methionine

874.30

19.5

91

1.74

0.0272

3.89

Sophorose minor

847.31

20.2

204

1.68

0.0346

3.01

  1. CON control piglets orally inoculated with PBS, LPS piglets received intraperitoneal injection (i.p.) with lipopolysaccharides (25 μg/kg body weight)
  2. Metabolites with VIP > 1.5 are shown in the Table. FC, fold-change of the peak intensity for the CON group against the LPS group (n = 6); P values were calculated according to Student’s t test
  3. RT, retention time; VIP, variable importance in projection
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Journal of Animal Science and Biotechnology

ISSN: 2049-1891