Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets

Table 3 The effects of GOS on colonic pH value, SCFAs and lactic acid concentrations in colonic digesta of LPS-challenged suckling piglets

Items	CON	LPS-CON	LPS-GOS	SEM	P-value
pH value	6.45 ^b	6.72 ^a	6.47 ^b	0.05	0.020
Acetate, μmol/g digesta	25.14 ^a	20.15 ^b	24.47 ^a	0.83	0.018
Propionate, μmol/g digesta	12.60	10.06	10.99	0.56	0.181
Isobutyrate, μmol/g digesta	1.19	1.10	1.16	0.03	0.533
Butyrate, μmol/g digesta	6.65 ^a	4.62 ^b	6.72 ^a	0.34	0.007
Isovalerate, μmol/g digesta	2.10	1.90	1.97	0.12	0.804
Valerate, μmol/g digesta	2.01	1.10	1.36	0.18	0.091
Total SCFAs, μmol/g digesta	49.69 ^a	38.93 ^b	46.68 ^a	1.57	0.006
Lactate, μmol/g digesta	1.58 ^ab	1.26 ^b	1.62 ^a	0.06	0.021

Values are expressed as mean ± SEM, n = 6. CON control group, LPS-CON piglets challenged with LPS, LPS-GOS piglets fed with GOS and challenged with LPS. P values < 0.05 were considered significant, P values between 0.05 and 0.10 were considered as a tendency. Different superscript lowercase letters on the same line indicate significant differences (P < 0.05)

ISSN: 2049-1891