Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets

Table 1 The effects of GOS on antioxidant properties in the colonic mucosa of LPS-challenged suckling piglets

Items	CON	LPS-CON	LPS-GOS	SEM	P-value
MDA, nmol/mg protein	1.20^b	1.73^a	1.25^b	0.09	0.014
ROS, U/mg protein	108.13^b	145.97^a	112.20^b	6.34	0.017
GSH-PX, U/mg protein	21.60^a	15.86^b	17.04^ab	0.91	0.013
SOD, U/mg protein	41.71^a	28.41^b	36.52^ab	1.84	0.004
T-AOC, U/mg protein	5.97^a	4.18^b	5.21^a	0.22	< 0.001

Values are expressed as mean ± SEM, n = 6. CON control group, LPS-CON piglets challenged with LPS, LPS-GOS piglets fed with GOS and challenged with LPS. MDA malondialdehyde, ROS reactive oxygen species, GSH-Px glutathione peroxidase, SOD superoxide dismutase, T-AOC total antioxidant capacity. P values < 0.05 were considered significant, P values between 0.05 and 0.10 were considered as a tendency. Different superscript lowercase letters on the same line indicate significant differences (P < 0.05)

ISSN: 2049-1891