Table 4 Candidate genes resided in ROH island associated with economic traits of animals
Breeds | OAR | Position, bp | Candidate genes | Gene function |
|---|---|---|---|---|
ALT, LTH | 1 | 250,958,731 ~ 251,069,283 | PCCB | Growth and carcass |
LTH, HLB,STG | 4 | 68,858,042 ~ 68,863,494 | HOXA10 | Fat deposition |
LTH, HLB, STG | 4 | 68,921,977 ~ 68,924,549 | HOXA3 | Embryo development |
TIB | 5 | 19,737,330 ~ 19,769,293 | P4HA2 | Hypoxic adaptation |
TIB | 5 | 19,956,144 ~ 19,958,155 | CSF2 | Immunity and inflammation response |
TIB | 5 | 19,971,457 ~ 19,973,243 | IL3 | Immunity regulation |
HLB, STG | 10 | 35,862,425 ~ 35,885,746 | LATS2 | Embryonic development |
HLB, STG | 10 | 36,045,326 ~ 36,103,818 | IFT88 | Inflammatory response |
HLB, STG | 10 | 36,253,000 ~ 36,253,785 | GJB6 | Body size and development |
HLB, STG | 10 | 36,271,774 ~ 36,272,454 | GJB2 | Body size and development |
HLB, STG | 10 | 36,304,573 ~ 36,305,769 | GJA3 | Body size and development |
ALT, LTH, HLB, STG, TIB | 12 | 78,543,637 ~ 78,552,280 | CSRP1 | Growth and carcass |
ALT, LTH, HLB, STG, TIB | 12 | 78,591,681 ~ 78,596,742 | TNNI1 | Growth, carcass and meat quality |
ALT, LTH, HLB, STG | 13 | 53,097,296 ~ 53,098,312 | NPBWR2 | Reproductive activity |
ALT, LTH,HLB, STG, TIB | 13 | 53,280,623 ~ 53,282,184 | ABHD16B | Male infertility |
ALT, LTH, HLB, STG, TIB | 13 | 53,482,080 ~ 53,488,365 | EEF1A2 | Muscle development and lipid metabolism |
LTH | 15 | 3,848,546 ~ 4,133,998 | PDGFD | Lipid metabolism |
LTH | 17 | 53,560,417 ~ 53,616,466 | P2RX7 | Final weight and backfat thickness |
LTH | 17 | 53,661,638 ~ 53,752,199 | IFT81 | Spermiogenesis and fertility |