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Table 7 Effect of dietary vitamin K (VK) supplementation and Salmonella Enteritidis (SE) challenge on serum biochemical indices of laying hens (n = 6)

From: Vitamin K alleviates bone calcium loss caused by Salmonella Enteritidis through carboxylation of osteocalcin

VK, mg/kg

SEc

Cad, mmol/L

CTe, pg/mL

PTHf, pg/mL

cOCg, ng/mL

ucOCh, ng/mL

cOC/(cOC + ucOC), %

Week 42

Week 44

Week 42

Week 44

Week 42

Week 44

Week 42

Week 44

Week 42

Week 44

Week 42

Week 44

0

–

5.83

3.47b

321.53

231.04

102.19

98.26

2.38

2.07

2.10

2.43

57.92

44.33

0

+

 

5.40a

 

330.98

 

99.39

 

1.87

 

2.46

 

43.90

2

–

5.03

4.66ab

270.89

262.15

67.43

92.20

2.32

2.45

1.54

1.45

59.75

63.70

2

+

 

4.57ab

 

301.62

 

81.93

 

2.76

 

1.39

 

67.64

 

SEMi

0.973

0.406

29.193

25.980

15.255

8.219

0.301

0.100

0.400

0.285

0.731

2.539

0

 

–

4.37

–

246.60b

–

98.64

–

1.99b

–

2.44a

–

44.16b

2

 

–

4.62

–

314.20a

–

88.78

–

2.52a

–

1.43b

–

64.69a

 

SEMi

–

0.287

–

17.770

–

5.897

–

0.073

–

0.179

–

2.273

 

–

–

4.06b

–

281.01

–

95.23

–

2.67

–

2.01

–

54.02

 

+

–

4.98a

–

284.71

–

90.66

–

2.76

–

1.92

–

51.81

 

SEMi

–

0.287

–

17.770

–

5.811

–

0.071

–

0.178

–

2.244

 

VK

0.622

0.661

0.345

0.022

0.248

0.20

0.898

< 0.001

0.424

0.005

0.220

0.001

P-values8

SE

–

0.032

–

0.973

–

0.60

–

0.662

–

0.959

–

0.611

 

VK × SE

–

0.019

–

0.260

–

0.513

–

0.051

–

0.861

–

0.530

  1. a, bMeans within a column with no common superscripts differ (P < 0.05)
  2. cSE Salmonella Enteritidis; −, without SE challenge; +, with SE challenge
  3. dCa Calcium
  4. eCT calcitonin
  5. fPTH Parathyroid hormone
  6. gcOC Carboxylated osteocalcin
  7. hucOC Undercarboxylated osteocalcin
  8. iSEM Pooled standard error of the mean
  9. 8P-values for main effect of VK, the main effect of SE challenge, and the interaction between the VK treatments and SE challenge