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Table 7 Effect of dietary vitamin K (VK) supplementation and Salmonella Enteritidis (SE) challenge on serum biochemical indices of laying hens (n = 6)

From: Vitamin K alleviates bone calcium loss caused by Salmonella Enteritidis through carboxylation of osteocalcin

VK, mg/kg SEc Cad, mmol/L CTe, pg/mL PTHf, pg/mL cOCg, ng/mL ucOCh, ng/mL cOC/(cOC + ucOC), %
Week 42 Week 44 Week 42 Week 44 Week 42 Week 44 Week 42 Week 44 Week 42 Week 44 Week 42 Week 44
0 5.83 3.47b 321.53 231.04 102.19 98.26 2.38 2.07 2.10 2.43 57.92 44.33
0 +   5.40a   330.98   99.39   1.87   2.46   43.90
2 5.03 4.66ab 270.89 262.15 67.43 92.20 2.32 2.45 1.54 1.45 59.75 63.70
2 +   4.57ab   301.62   81.93   2.76   1.39   67.64
  SEMi 0.973 0.406 29.193 25.980 15.255 8.219 0.301 0.100 0.400 0.285 0.731 2.539
0   4.37 246.60b 98.64 1.99b 2.44a 44.16b
2   4.62 314.20a 88.78 2.52a 1.43b 64.69a
  SEMi 0.287 17.770 5.897 0.073 0.179 2.273
  4.06b 281.01 95.23 2.67 2.01 54.02
  + 4.98a 284.71 90.66 2.76 1.92 51.81
  SEMi 0.287 17.770 5.811 0.071 0.178 2.244
  VK 0.622 0.661 0.345 0.022 0.248 0.20 0.898 < 0.001 0.424 0.005 0.220 0.001
P-values8 SE 0.032 0.973 0.60 0.662 0.959 0.611
  VK × SE 0.019 0.260 0.513 0.051 0.861 0.530
  1. a, bMeans within a column with no common superscripts differ (P < 0.05)
  2. cSE Salmonella Enteritidis; −, without SE challenge; +, with SE challenge
  3. dCa Calcium
  4. eCT calcitonin
  5. fPTH Parathyroid hormone
  6. gcOC Carboxylated osteocalcin
  7. hucOC Undercarboxylated osteocalcin
  8. iSEM Pooled standard error of the mean
  9. 8P-values for main effect of VK, the main effect of SE challenge, and the interaction between the VK treatments and SE challenge