Table 5 Effects of genotype and substance delivered in ovo, and their interaction on gene expression and methylation signatures in spleen of Ross and GP chickens
Gene | Gene expression | Gene methylation | ||||
|---|---|---|---|---|---|---|
Genotype | Substance | Genotype × Substance | Genotype | Substance | Genotype × Substance | |
CD72 | ns | ns | ns | ns | ns | ns |
CXCR5 | ns | ns | ns | ns | ns | ns |
NFATC1 | < 0.05 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.01 | < 0.01 |
SYK | < 0.01 | ns | ns | < 0.0001 | ns | < 0.01 |
CYR61 | ns | < 0.0001 | < 0.0001 | ns | ns | ns |
NR4A3 | ns | < 0.0001 | < 0.0001 | ns | ns | ns |
SERPING1 | < 0.001 | < 0.0001 | < 0.0001 | ns | ns | ns |
TNFRSF14 | ns | < 0.0001 | < 0.0001 | ns | ns | < 0.05 |
IKZF1 | < 0.0001 | < 0.0001 | < 0.0001 | ns | < 0.01 | < 0.01 |
KLHL6 | < 0.05 | ns | ns | < 0.0001 | ns | ns |
ANGPTL4 | < 0.0001 | < 0.001 | < 0.0001 | ns | ns | ns |