Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway

Table 4 Effects of dietary PQQ supplementation on antioxidant activities in the intestinal tissues of weaned pigs¹

Items	Pyrroloquinoline quinone disodium levels,%				SEM	P-value
Items	0	0.15	0.3	0.45	SEM	ANOVA	Linear	Quadratic
Duodenum
SOD, U/mg	95.74	92.16	111.52	98.04	5.98	0.15	0.34	0.42
GSH-Px, U/mg	85.20	100.79	105.69	103.41	5.09	0.05	0.51	0.10
MDA, nmol/mg	0.67	0.90	0.68	0.68	0.06	0.05	0.08	0.09
CAT, U/mg	2.14	1.83	2.10	2.13	0.36	0.92	0.89	0.65
Jejunum
SOD, U/mg	95.53^b	106.08^ab	114.80^a	116.16^a	4.60	0.02	< 0.01	0.33
GSH-Px, U/mg	102.32^b	114.87^a	119.05^a	109.62^ab	2.75	< 0.01	0.10	0.57
MDA, nmol/mg	0.79^a	0.72^ab	0.45^b	0.40^b	0.09	0.01	< 0.01	0.87
CAT, U/mg	2.22	1.86	2.54	2.43	0.39	0.64	0.46	0.75
Ileum
SOD, U/mg	87.92	86.71	85.39	89.29	3.42	0.87	0.86	0.46
GSH-Px, U/mg	103.08	98.32	113.41	108.90	5.50	0.27	0.34	0.98
MDA, nmol/mg	1.35^a	0.93^b	0.81^b	0.86^b	0.11	0.01	0.20	0.05
CAT, U/mg	1.16	1.26	1.29	1.25	0.03	0.08	0.08	0.05

¹ SEM standard error of the mean; the values are means ± SEM; 6 replicates. The linear and quadratic differences are with respect to pyrroloquinoline quinone disodium levels. Means within a row lacking a common letter are significantly different (P < 0.05). Antioxidant activities are expressed per mg of protein

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