Fig. 4From: Protective effects of sodium butyrate on rotavirus inducing endoplasmic reticulum stress-mediated apoptosis via PERK-eIF2α signaling pathway in IPEC-J2 cellsThe effects of SB on proliferation and apoptosis in RV-infected IPEC-J2 cells. a The change of cell viability after treatment with SB (0, 1, 2, 4, 8, 16 mmol/L) for 24 h. b The IPEC-J2 cells were pretreated with SB (0, 1, 2, 4, 8, 16 mmol/L) for 24 h, followed by challenge with or without RV (10 MOI) for 1 h, and then incubated with DMEM/F12 for a further 24 h. Cell viability was detected by CCK-8 assay. c Apoptotic populations of cells double stained with PI- and FITC-labeled Annexin V were measured by flow cytometry. *P < 0.05, **P < 0.01, data are expressed as means ± S.D. from three independent experiments at leastBack to article page