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Table 5 GO annotation of upregulated proteins in broiler chickens in the immune stress group

From: Molecular mechanisms of growth depression in broiler chickens (Gallus Gallus domesticus) mediated by immune stress: a hepatic proteome study

GO ID

GO Term

Term P- value

Associated proteins enriched

Biological process

 GO:0009617

Response to bacterium

81.0E-9

AvBD1, AvBD2, AvBD7, CATH2, CATH3, CD36, FGB, LY86, LYN, RSFR, TAP2

 GO:0098542

Defense response to other organism

1.4E-6

AvBD1, AvBD2, AvBD7, CATH2, CATH3, CD36, FADD, FGB, OASL, RSFR

 GO:0042742

Defense response to bacterium

87.0E-9

AvBD1, AvBD2, AvBD7, CATH2, CATH3, CD36, FGB, RSFR

 GO:0050829

Defense response to Gram-negative bacterium

33.0E-6

AvBD7, CATH2, CATH3, RSFR

 GO:0050829

Defense response to Gram-positive bacterium

79.0E-6

CATH2, CATH3, CD36, RSFR

 GO:0016054

Organic acid catabolic process

3.3E-3

AGXT2, HIBCH, OAT, SLC27A4

 GO:0009063

Cellular amino acid catabolic process

3.3E-3

AGXT2, HIBCH, OAT

 GO:0046395

Carboxylic acid catabolic process

3.3E-3

AGXT2, HIBCH, OAT, SLC27A4

 GO:1901606

Alpha-amino acid catabolic process

2.4E-3

AGXT2, HIBCH, OAT

 GO:0051279

Regulation of release of sequestered calcium ion into cytosol

1.5E-3

CLIC2, LYN, SRI

 GO:0097553

Calcium ion transmembrane import into cytosol

5.6E-3

CLIC2, LYN, SRI

 GO:0032845

Negative regulation of homeostatic process

2.1E-3

CLIC2, FADD, LYN, SRI

 GO:0051238

Sequestering of metal ion

8.4E-3

CLIC2, LYN, SRI

 GO:0032387

Negative regulation of intracellular transport

10.0E-3

CD36, CLIC2, SRI

 GO:1903650

Negative regulation of cytoplasmic transport

5.3E-3

CD36, CLIC2, SRI

 GO:0051282

Regulation of sequestering of calcium ion

5.6E-3

CLIC2, LYN, SRI

 GO:0051208

Sequestering of calcium ion

5.9E-3

CLIC2, LYN, SRI

 GO:0051283

Negative regulation of sequestering of calcium ion

5.6E-3

CLIC2, LYN, SRI

 GO:0090279

Regulation of calcium ion import

3.5E-3

CLIC2, LYN, SRI

 GO:0010522

Regulation of calcium ion transport into cytosol

2.2E-3

CLIC2, LYN, SRI

 GO:1903169

Regulation of calcium ion transmembrane transport

3.7E-3

CLIC2, LYN, SRI

 GO:0060402

Calcium ion transport into cytosol

8.0E-3

CLIC2, LYN, SRI

 GO:0051209

Release of sequestered calcium ion into cytosol

5.6E-3

CLIC2, LYN, SRI

 GO:1902656

Calcium ion import into cytosol

6.2E-3

CLIC2, LYN, SRI

 GO:0050818

Regulation of coagulation

460.0E-6

CD36, FGB, FGG, LYN

 GO:0072376

Protein activation cascade

1.2E-3

C4, FGB, FGG

 GO:0007599

Hemostasis

970.0E-6

CD36, FGA, FGB, FGG, LYN

 GO:1900046

Regulation of hemostasis

320.0E-6

CD36, FGB, FGG, LYN

 GO:0007596

Blood coagulation

930.0E-6

CD36, FGA, FGB, FGG, LYN

 GO:0030168

Platelet activation

590.0E-6

FGA, FGB, FGG, LYN

 GO:0071219

Cellular response to molecule of bacterial origin

10.0E-3

CD36, LY86, LYN

 GO:0030193

Regulation of blood coagulation

320.0E-6

CD36, FGB, FGG, LYN

 GO:0061041

Regulation of wound healing

1.4E-3

CD36, FGB, FGG, LYN

 GO:0070527

Platelet aggregation

1.2E-3

FGB, FGG, LYN

 GO:0071222

Cellular response to LPS

9.8E-3

CD36, LY86, LYN

 GO:0002793

Positive regulation of peptide secretion

1.8E-3

FGB, FGG, SRI

 GO:0046887

Positive regulation of hormone secretion

5.6E-3

FGB, FGG, SRI

 GO:0008625

Extrinsic apoptotic signaling pathway via death domain receptors

250.0E-6

FADD, FGB, FGG, STK4

 GO:1904019

Epithelial cell apoptotic process

4.8E-3

FGB, FGG, STK4

 GO:0090277

Positive regulation of peptide hormone secretion

1.8E-3

FGB, FGG, SRI

 GO:1902041

Regulation of extrinsic apoptotic signaling pathway via death domain receptors

63.0E-6

FADD, FGB, FGG, STK4

Pathway

 GO:0000280

Valine, leucine and isoleucine degradation

3.1E-3

AGXT2, HIBCH, IL4I1