Fig. 5From: Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression, evoking oxidative stress, and activating inflammation and apoptosisThe content of the pro-inflammatory cytokines IL-1β, IL-6, IL-8, IL-12, IL-17, and TNF-α; anti-inflammatory cytokines IL-10, IL-13, and TGF-β; transcription factors NF-κB and HIF-1α; NF-κB p65 and COX-2; and the relative mRNA levels of inflammatory genes in the spleen in the Se-adequate group and Se-deficient group. Values are means ± SEM, n = 12. * Different from Se-A, P < 0.05; ** different from Se-A, P < 0.01Back to article page