Table 1 Effect of HS and MOLP supplementation on the log fold change (logFC) of differentially expressed genes (DEGs) in pairwise comparison (HS vs. CON, HSM vs. CON and HSM vs. HS) that encode proteins in allograft rejection pathway

Inflammatory factor

IFNG

3.97

< 0.0001

0.000223

Interferon gamma precursor

IL12B

−3.33

< 0.0001

−4.57

< 0.0001

Interleukin-12 subunit beta

IGGC

1.81

< 0.0001

1.35

< 0.0001

Ig gamma chain C region

CD40LG

11.16

0.004

10.92

0.004

CD40 ligand

PRF1

−1.01

< 0.0001

< 0.0001

Perforin-1

LOC100101600 (granzyme H)

−2.44

< 0.0001

−3.02

< 0.0001

Granzyme H

LOC100101600 (granzyme B)

< 0.0001

Duodenase-1

IL10

0.0014

Interleukin-10 isoform X1

CD86

−1.72

0.0004

0.0055

T-lymphocyte activation antigen CD86 precursor

MHC

(major histocompatibility complex)

RLA-DMB

< 0.0001

Histocompatibility antigen DM heterodimer light chain-like precursor

LOC100351416

−1.18

< 0.0001

< 0.0001

HLA class II histocompatibility antigen, DO beta chain isoform X2

LOC100351163

1.44

< 0.0001

< 0.0001

HLA class II histocompatibility antigen, DQ beta 1 chain isoform X2

LOC100343144

1.12

< 0.0001

< 0.0001

SLA class II histocompatibility antigen, DQ haplotype D alpha chain isoform X2

RLA-DRB1

< 0.0001

HLA class II histocompatibility antigen, DRB1–4 beta chain

LOC100349667

−1.12

0.021

HLA class II histocompatibility antigen, DRB1–1 beta chain isoform X1

RLA-A3

< 0.0001

MHC class I antigen-like isoform X1

LOC100349247

−1.36

< 0.0001

< 0.0001

HLA class I histocompatibility antigen, B-7 alpha chain isoform X1

LOC100328967

< 0.0001

RLA class I histocompatibility antigen, alpha chain 19–1 precursor

LOC100349085

−1.97

< 0.0001

< 0.0001

RLA class I histocompatibility antigen, alpha chain 11/11

LOC100338822

1.83

< 0.0001

1.38

< 0.0001

RLA class I histocompatibility antigen, alpha chain 11/11