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Fig. 7 | Journal of Animal Science and Biotechnology

Fig. 7

From: Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis

Fig. 7

TLR4 overexpression enhances cathepsin B activity. a The relative cathepsin B activity of transgenic (TG) and wild-type (WT) monocytes was assessed following infection with E. coli for different times (MOI = 10). b Monocytes were pretreated with the control (DMSO) or various inhibitors for 2 h, and after 30 min of E. coli infection (MOI = 10), cathepsin B activity was compared. All data are presented as the mean ± SD, n ≥ 3; *P < 0.05, **P < 0.01. DMSO, dimethyl sulfoxide; MOI, multiplicity of infection

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