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Fig. 4 | Journal of Animal Science and Biotechnology

Fig. 4

From: Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis

Fig. 4

TLR4 overexpression promotes the internalization of E. coli through caveolae-mediated endocytosis. a The activation of proteins involved in caveolae-mediated endocytosis signalling in transgenic (TG) and wild-type (WT) monocytes was detected by immunoblotting at different time points after E. coli infection. b, c The phosphorylation levels of Src and CAV1 were quantified based on immunoblotting. d, e The protein expression levels of Src and CAV1 were quantified based on immunoblotting. All data are presented as the mean ± SD, n ≥ 3; *P < 0.05, **P < 0.01. GAPDH was used for normalization

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Journal of Animal Science and Biotechnology

ISSN: 2049-1891