MYOD1 inhibits avian adipocyte differentiation via miRNA-206/KLF4 axis

Wang, Zheng; Zhao, Qiangsen; Li, Xiaoqin; Yin, Zhongtao; Chen, Sirui; Wu, Sen; Yang, Ning; Hou, Zhuocheng

doi:10.1186/s40104-021-00579-x

Journal of Animal Science and Biotechnology

Table 1 GO enrichment analysis of DEGs in MYOD1^OE, MYOD1^NC, and MYOD1^KO cells

From: MYOD1 inhibits avian adipocyte differentiation via miRNA-206/KLF4 axis

	Up-regulated	Gene count	Log (q-value)	Down-regulated	Gene count	Log (q-value)
MYOD1^OE vs. MYOD1^KO (day 0)	blood vessel development	74	−11.19	cell involved in differentiation	25	−1.35
	muscle structure development	64	9.51	extracellular matrix organization	38	−1.35
	heart development	56	−8.84	ATP metabolic process	21	−1.35
	actin cytoskeleton organization	60	−7.72	inorganic cation transmembrane transport	36	−1.12
	muscle tissue development	41	−6.50	developmental growth	30	−0.66
MYOD1^KO vs. MYOD1^NC (day 0)	regulation of cell morphogenesis	18	−3.09	regulation of system process	44	−8.02
	positive regulation of cell development	17	−2.34	skeletal system development	35	−5.05
	cell involved in differentiation	19	−2.19	muscle structure development	37	−3.82
	regulation of MAPK cascade	18	−1.89	heart development	34	−3.82
	regulation of lipid metabolic process	11	−1.09	muscle system process	29	−3.66
MYOD1^OE day 5 vs. day 0	nuclear division	70	−13.19	actin cytoskeleton organization	146	−23.46
	ncRNA metabolic process	78	−10.61	heart development	128	−21.58
	DNA replication	48	−9.70	skeletal system development	118	−20.87
	regulation of cell cycle process	83	−5.79	extracellular structure organization	95	−16.49
	ribosomal large subunit biogenesis	17	−4.12	muscle structure development	126	−15.92
MYOD1^NC day 5 vs. day 0	nuclear division	59	−21.11	extracellular matrix organization	46	−11.38
	cell division	71	−21.11	heart development	52	−8.01
	lipid biosynthetic process	40	−2.74	muscle structure development	55	−7.35
	regulation of MAPK cascade	36	−1.33	skeletal system development	45	−6.29
	glycerophospholipid metabolic process	19	−1.72	regulation of lipid metabolic process	35	−4.68
MYOD1^KO day 5 vs. day 0	cell division	68	−6.78	extracellular structure organization	66	−8.36
	protein autophosphorylation	22	−4.05	DNA replication	44	−4.73
	mitotic nuclear division	46	−4.02	skeletal system development	61	−3.78
	lipid biosynthetic process	40	−2.74	phospholipid metabolic process	53	−3.78
	regulation of cell cycle process	64	−2.13	muscle structure development	56	−0.89

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ISSN: 2049-1891

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