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Table 2 The effect of dietary LNT supplementation and/or RV challenge on the immunoglobulin, rotavirus-antibody, rotavirus non-structural protein 4 and/or interferon-β concentrations in serum and jejunal mucosa of weaned pigs

From: Lentinan administration alleviates diarrhea of rotavirus-infected weaned pigs via regulating intestinal immunity

 

− RV

+ RV

P value

CON

LNT

CON

LNT

RV

LNT

LNT × RV

Serum

 IgM, mg/mL

0.17 ± 0.02c

0.24 ± 0.01b

0.26 ± 0.01b

0.35 ± 0.03a

<  0.05

<  0.05

0.77

 IgG, mg/mL

1.26 ± 0.04b

1.49 ± 0.10a

1.59 ± 0.06a

1.64 ± 0.08a

0.07

<  0.05

0.25

 IgA, μg/mL

68.58 ± 2.50c

73.23 ± 1.54b

76.25 ± 1.21ab

81.24 ± 1.21a

<  0.05

<  0.05

0.92

 RV-Ab, ng/L

17.23 ± 2.07c

18.29 ± 0.99c

22.14 ± 1.07b

26.79 ± 1.15a

<  0.05

<  0.05

<  0.05

Jejunal mucosa

 NSP4, ng/mg protein

8.60 ± 0.61c

8.01 ± 0.56c

23.90 ± 0.63a

14.15 ± 0.59b

<  0.05

<  0.05

<  0.05

 sIgA, μg/mg protein

19.25 ± 1.23b

25.17 ± 1.52a

15.23 ± 0.82c

19.72 ± 0.92b

<  0.05

<  0.05

0.58

 RV-Ab, ng/mg protein

7.71 ± 0.57b

8.79 ± 0.72ab

8.82 ± 1.04ab

9.80 ± 0.55a

<  0.05

<  0.05

0.86

 IFN-β, pg/mg protein

225.31 ± 26.48c

353.65 ± 18.58b

401.87 ± 25.57b

508.88 ± 16.95a

<  0.05

< 0.05

0.64

  1. − RV infusing the essential medium, + RV infusing the porcine rotavirus, CON basal diet, LNT LNT-supplemented diet, IgA immunoglobulin A, IgG immunoglobulin G, IgM immunoglobulin M, RV-Ab rotavirus-antibody, NSP4 rotavirus non-structural protein 4, sIgA secretory immunoglobulin A, IFN-β interferon-β
  2. a, b, c Mean values within a row with different superscript letters were significantly different (P < 0.05)