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Table 2 The effect of dietary LNT supplementation and/or RV challenge on the immunoglobulin, rotavirus-antibody, rotavirus non-structural protein 4 and/or interferon-β concentrations in serum and jejunal mucosa of weaned pigs

From: Lentinan administration alleviates diarrhea of rotavirus-infected weaned pigs via regulating intestinal immunity

  − RV + RV P value
CON LNT CON LNT RV LNT LNT × RV
Serum
 IgM, mg/mL 0.17 ± 0.02c 0.24 ± 0.01b 0.26 ± 0.01b 0.35 ± 0.03a <  0.05 <  0.05 0.77
 IgG, mg/mL 1.26 ± 0.04b 1.49 ± 0.10a 1.59 ± 0.06a 1.64 ± 0.08a 0.07 <  0.05 0.25
 IgA, μg/mL 68.58 ± 2.50c 73.23 ± 1.54b 76.25 ± 1.21ab 81.24 ± 1.21a <  0.05 <  0.05 0.92
 RV-Ab, ng/L 17.23 ± 2.07c 18.29 ± 0.99c 22.14 ± 1.07b 26.79 ± 1.15a <  0.05 <  0.05 <  0.05
Jejunal mucosa
 NSP4, ng/mg protein 8.60 ± 0.61c 8.01 ± 0.56c 23.90 ± 0.63a 14.15 ± 0.59b <  0.05 <  0.05 <  0.05
 sIgA, μg/mg protein 19.25 ± 1.23b 25.17 ± 1.52a 15.23 ± 0.82c 19.72 ± 0.92b <  0.05 <  0.05 0.58
 RV-Ab, ng/mg protein 7.71 ± 0.57b 8.79 ± 0.72ab 8.82 ± 1.04ab 9.80 ± 0.55a <  0.05 <  0.05 0.86
 IFN-β, pg/mg protein 225.31 ± 26.48c 353.65 ± 18.58b 401.87 ± 25.57b 508.88 ± 16.95a <  0.05 < 0.05 0.64
  1. − RV infusing the essential medium, + RV infusing the porcine rotavirus, CON basal diet, LNT LNT-supplemented diet, IgA immunoglobulin A, IgG immunoglobulin G, IgM immunoglobulin M, RV-Ab rotavirus-antibody, NSP4 rotavirus non-structural protein 4, sIgA secretory immunoglobulin A, IFN-β interferon-β
  2. a, b, c Mean values within a row with different superscript letters were significantly different (P < 0.05)