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Table 3 Blood parameters in response to an intramammary inflammatory challenge with Streptococcus uberis in animal fed a control diet (CON), or a diet supplemented with a Saccharomyces cerevisiae fermentation product (NTK)

From: Feeding a Saccharomyces cerevisiae fermentation product improves udder health and immune response to a Streptococcus uberis mastitis challenge in mid-lactation dairy cows

Parameter2 TRT1 SEM P-value
CON NTK TRT Time TRT×Time
Phase 2
Metabolism
  Glucose, mmol/L 4.68 4.74 0.12 0.70 <.0001 0.99
  NEFA, mmol/L 0.119 0.124 0.013 0.81 0.04 0.16
  BHB, mmol/L 0.513 0.519 0.031 0.87 <.0001 0.75
  Cholesterol, mmol/L 5.65 5.19 0.32 0.32 0.0004 0.92
  Urea, mmol/L 4.55 5.00 0.17 0.08 <.0001 0.40
  Creatinine, μmol/L 79.33 80.05 1.91 0.79 <.0001 0.05
Inflammation and acute phase proteins
  IL-1β, pg/mL 80.93 47.44 24.7 0.35 0.13 0.05
  IL-6, pg/mL 284.7 293.3 44.2 0.89 0.16 0.76
  MPO, U/L 433.8 427.4 18.5 0.81 <.0001 0.27
  Haptoglobin, g/L 0.555 0.546 0.101 0.94 <.0001 0.33
  Albumins, g/L 37.84 37.93 0.52 0.90 <.0001 0.85
  Bilirubin, total, μmol/L 2.38 2.12 0.13 0.17 0.06 0.11
  Ceruloplasmin, μmol/L 3.18 3.14 0.24 0.90 <.0001 0.79
Oxidative status
  ROMt, mg H2O2/100 mL 16.57 16.26 0.86 0.80 <.0001 0.68
  NOx, μmol/L 21.91 21.55 0.50 0.62 0.01 0.93
  NO2, μmol/L 5.33 5.31 0.29 0.96 0.04 0.74
  NO3, μmol/L 16.72 16.15 0.36 0.28 0.15 0.97
  FRAP, μmol/L 132.3 134.2 5.3 0.80 <.0001 0.35
  Paraoxonase, U/mL 91.1 90.09 4.74 0.88 0.001 0.95
Liver enzymes
  Alkaline phosphatase, U/L 56.80 63.89 4.53 0.28 <.0001 0.54
  AST, U/L 88.85 115.19 10.84 0.10 <.0001 0.40
  GGT, U/L 31.32 38.06 4.15 0.27 <.0001 0.89
Minerals
  Ca, mmol/L 2.43a 2.55b 0.03 0.01 0.009 0.28
  Cl, mmol/L 101.8 101.5 0.6 0.75 <.0001 0.34
  K, mmol/L 4.55 4.57 0.05 0.80 0.004 0.83
  Mg, mmol/L 1.06 1.01 0.02 0.09 <.0001 0.71
  Na, mmol/L 142.8 143.7 0.4 0.17 <.0001 0.05
  P, mmol/L 1.97 1.94 0.08 0.78 0.10 0.70
  Zn, μmol/L 9.84 11.20 1.06 0.37 <.0001 0.66
  1. 1TRT Treatment, CON Control, NTK NutriTek® supplemented group (19 g/d)
  2. 2NEFA Non-esterified fatty acids, BHB β-hydroxy butyrate, MPO Myeloperoxidase, IL1β and IL6 Interleukin 1 beta and 6, NOx Nitric oxides, FRAP Ferric reducing ability of plasma, ROMt Total reactive oxygen metabolites, GGT γ-glutamyl transferase, AST Aspartate aminotransferase