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Fig. 5 | Journal of Animal Science and Biotechnology

Fig. 5

From: Comprehensive evaluation of the metabolic effects of porcine CRTC3 overexpression on subcutaneous adipocytes with metabolomic and transcriptomic analyses

Fig. 5

CRTC3 overexpression regulates FA and GP related metabolic pathways. a, b. The log2-fold changes in FA metabolites (a) and GP metabolites (b) following CRTC3 overexpression. Metabolites are ranked according to P value. c, d. Heatmaps showing the selected differentially expressed genes (DEGs) involved in FA (c) and GP (d) metabolism in CRTC3-overexpressing adipocytes. e. The selected metabolic reactions of lipids (FAs and GPs) from the KEGG analysis, along with interaction of altered lipid metabolites and related genes that were significantly regulated in adipocytes overexpressing CRTC3. Metabolites are indicated by circles (|log2-fold change| > log2 1; P value< 0.05), and genes are indicated by squares (|log2-fold change| > log2 1.5; padj< 0.05). Red indicates an increase or upregulation, blue indicates a decrease or downregulation, and gray indicates undetected. Reaction directions are indicated according to KEGG Mapper (the arrows do not necessarily correspond to reaction reversibility). The dashed lines represented an indirect connection

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