Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics

Table 5 The most enriched GO biological process terms assigned to the 87 up-regulated and 111 down-regulated transcripts in gastrocnemius muscle of pigs of group IM10 compared with group CON^a

GO biological process term	Number of genes	P-value	Fold enrichment
Up-regulated transcripts
G-protein coupled receptor signaling pathway	11	0.004	2.8
Phagocytosis	3	0.034	10.1
Glucose 6-phosphate metabolic process	2	0.036	54.0
Down-regulated transcripts
Response to lipid	7	0.009	3.8
Neurological system process	11	0.011	2.5
Adult behavior	4	0.013	8.0
Neuron development	8	0.019	2.9
System process	13	0.020	2.0
Response to retinoic acid	3	0.021	13.2
Neuron projection development	7	0.026	3.0
Single-organism behavior	5	0.026	4.3
Adult locomotory behavior	3	0.037	9.7
Sensory perception of chemical stimulus	7	0.038	2.8
Axon development	5	0.039	3.8
Sensory perception of smell	5	0.041	3.8
Response to organic substance	13	0.042	1.8
Kidney development	4	0.049	4.8

^aGO terms are sorted by their enrichment P-value in ascending order. Only GO terms with EASE scores (enrichment P-value) < 0.05 are shown
Abbreviations: CON control group; GO gene ontology; IM10 insect meal 10% group

ISSN: 2049-1891