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Table 2 The published functions of miR-365-3p and its validated targets

From: MicroRNA bta-miR-365-3p inhibits proliferation but promotes differentiation of primary bovine myoblasts by targeting the activin A receptor type I

Target genes

Genes name

Functions

References PMID

HDAC4

Histone deacetylase 4

Stimulate chondrocyte differentiation in chicken or mouse/osteoarthritis development in human

21856783

HDAC4

Histone deacetylase 4

Osteoarthiritis development in human

27023516

TTF1

Thyroid transcription factor1

Regulate lung cancer

22185756 and 26337230

CycD1/Bcl2

Cyclin D1/Bcl apoptosis regulator 2

Regulate colon cancer

22072615

SHC1

Src homology domain containing 1

Gemcitabine Regulate pancreatic cancer

24216611

NFIB

Nuclear factor I/B

Promote cutaneous squamous cell carcinoma

24949940

CycD1/cdc25A

Cyclin D1

Contribute to gastric tumorigenesis

24149576

CycD1

Cyclin D1

Inhibit vascular smooth muscle cell proliferation

24819721 and 24936138

Pax6

Paired box 6

Regulate human retinoblastoma cells

23660406

Not clearly

 

Transport-related stress in turkeys

26760121

Kcnh2

Potassium voltage-gated channel subfamily H member 2

Regulate nociceptive behaviors

26937014

IL-6

Interleukin-6

Host defense

21518763

Bcl-2

Bcl apoptosis regulator 2

Response low-density lipoprotein stimulation

21640710