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Table 8 Summary of studies in periparturient dairy cows investigating the effects of supplemental phytoproducts on cow metabolism

From: Role of nutraceuticals during the transition period of dairy cows: a review

Nutraceutical Treatment Period Tissue/Cells Main outcome Reference
EO mix (thymol, eugenol, vanillin, guiacol, limonene 1 g/cow/d From −21 d to 42 d relative to calving Blood γ-glutamyltransferase increase [137]
EO (curcum oleoresin or garlic excract or capsicum oleoresin) 2 g/cow/d 9 d treatment Blood Subtle or no effect on blood cells, nutrient digestibility, antioxidant status and mRNA liver enzymes expression. Immune-stimulatory effect by CD4 cells activation and expansion [142]
EO (allicin or pinene) 5 g/cow/d Allium sativum standardized at 1.5% of allicin; 2 g/cow Juniper communis standardized at 35% pinene 21 d Rumen DM, OM and CP ruminal truly digestibility increase [143]
Quebracho tannin 90 g/cow/d 6 weeks (− 3 before and + 3 after calving) Blood Antiketogenic effect decreasing BHB [144]
Tea saponin 20, 30, 40 g/cow/d 8 weeks treatment   Tea saponin may reduce oxidative stress and improve immune system [140]
  1. EO essential oil, DM and DMI dry matter and dry matter intake, respectively, CD4 cluster differentiation-4, OM organic matter, CP crude protein, BHB beta-hydroxybutyrate