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Table 3 Milk fat globule membrane proteins that were present at lower abundance in colostrum and milk collected at milkings 1, 2, 4, and 14 postpartum from primiparous (PP; n = 10) cows compared with multiparous (MP, n = 10) cows. Average abundance across milkings is presented within parity

From: Shifts in the Holstein dairy cow milk fat globule membrane proteome that occur during the first week of lactation are affected by parity

Accession number

Description

MP

PP

P-value

Value

SE

Value

SE

A0A0N4STN1

Cathelicidin-1-like

123.6

7.5

64.7

7.5

<.0001

F1MHS5

Protein S100-A9

126.6

12.6

51.8

12.6

<.0001

F1N726

Glycoprotein 2

128.6

8.2

59.3

8.2

<.0001

G3MXB5

Immunoglobulin IgA heavy chain constant region, partial

129.1

7.6

40.4

7.6

<.0001

P28782

Protein S100-A8

125.7

12.0

49.6

12.0

<.0001

P79105

Protein S100-A12

125.7

10.0

55.0

10.0

<.0001

P81265

Polymeric immunoglobulin receptor

123.9

7.1

54.5

7.1

<.0001

Q3SYR8

Immunoglobulin J chain

114.5

4.7

63.2

4.7

<.0001

F1MH40

IGK protein

116.7

10.5

55.8

10.5

0.0001

G3N2D7

Immunoglobulin light chain, partial

91.4

4.8

63.6

4.8

0.0001

F1MX83

Protein S100

126.6

8.4

79.1

8.4

0.0002

Q1JPB0

Leukocyte elastase inhibitor

117.1

9.7

62.2

9.7

0.0002

E1BF48

CD177 molecule

117.8

12.9

48.5

12.9

0.0003

G5E5V1

Immunoglobulin iota chain-like, partial (TPA)

104.4

8.7

57.2

8.7

0.0003

E1BGN3

Histone H3

114.7

13.4

44.9

13.4

0.0005

A0A0A0MP90

Histone H2A

118.2

13.9

47.8

13.9

0.0006

P24627

Lactotransferrin

109.2

12.4

47.7

12.4

0.0008

P56425

Cathelicidin-7

121.9

11.3

66.1

11.3

0.0008

P60712

Actin, cytoplasmic 1

117.0

8.3

75.6

8.3

0.0008

F1MUD2

Histone H2B

122.6

17.0

41.3

17.0

0.0011

Q17QG8

Histone H2A

110.6

13.5

46.1

13.6

0.0012

F1N514

CD5 antigen-like precursor

107.0

6.9

75.2

6.9

0.0018

P62803

Histone H4

123.7

16.0

50.4

16.0

0.0018

G5E513

IgM heavy chain constant region, secretory form, partial

109.7

7.6

76.1

7.6

0.0025

F1N650

Annexin

118.1

13.8

57.6

13.8

0.0027

G5E5T5

Immunoglobulin M heavy chain secretory form

109.6

7.1

78.7

7.1

0.0030

F1N5M2

Vitamin D-binding protein

103.8

7.7

72.1

7.7

0.0048

F1MCF8

IGL@ protein

104.1

13.0

51.1

13.0

0.0053

P48616

Vimentin

112.9

9.1

75.7

9.1

0.0053

G3MWV5

Histone cluster 1 H1 family member e

108.0

17.5

38.4

17.6

0.0065

F1N1I6

Gelsolin

110.8

6.4

85.6

6.4

0.0070

A0A140T881

Apolipoprotein E

113.9

6.2

89.4

6.2

0.0071

A6QNL0

Monocyte differentiation antigen CD14

125.9

7.4

97.2

7.4

0.0074

F1MLW8

Immunoglobulin lambda-1 light chain-like isoform X5

99.3

10.0

62.1

10.0

0.0108

G3N0V2

Keratin 1

110.8

5.9

88.9

5.9

0.0112

G3X7A5

Complement C3

111.1

8.6

82.7

8.6

0.0217

P01888

Beta-2-microglobulin

112.3

18.4

51.9

18.5

0.0241

G3N0V0

Secreted immunoglobulin gamma2 heavy chain constant region, partial

104.1

16.7

54.0

16.7

0.0373

G5E604

TPA: immunoglobulin iota chain-like

95.7

8.6

70.7

8.6

0.0435