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Table 8 Plasma concentrations of oxidized linoleic acid metabolites derived from multiple sources and ratios of select upstream:downstream metabolites in control ewes and ewes treated with 90 mg meloxicam on d 1 and 4 after lambing (mean ± SEM; μmol/L)

From: Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes

    P-values1
Oxylipid or Ratio2CONMELSEMTrtCovCov × trtLambsHpcov × trt
9-HODE52.544.94.2NS0.010.070.03<  0.01
9-oxoODE13.9912.371.24NSNSNS0.010.02
13-HODE133.0124.88.45NSNS<  0.01NSNS
13-oxoODE1.902.550.31NSNSNSNSNS
9-HODE:9-oxoODE33.353.590.17NSNS0.060.06<  0.10
13-HODE:13-oxoODE462.351.15.4NSNS0.04NSNS
9,10-EpOME:9,10-DiHOME0.370.460.030.06
  1. 1NS = P > 0.10
  2. 2HODE Hydroxyoctadecadienoic acid, oxoODE Oxooctadecadienoic acid, EpOME Epoxyoctadecenoic acid, DiHOME Dihydroxyoctadecenoic acid
  3. 3Cov × cov × trt: P = 0.06
  4. 4Cov × cov: P = 0.09; Cov × cov × trt: P = 0.04