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Table 5 Lipoxygenase-derived oxylipids in plasma of control ewes and ewes treated with 90 mg meloxicam on d 1 and 4 after lambing (mean ± SEM; μmol/L)

From: Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes

 

P-values1

Oxylipid2

Substrate3

CON

MEL

SEM

Trt

Cov

Cov × trt

Lambs

Hpcov × trt

5-HETE

ArA

0.10

0.29

0.22

NS

NS

NS

0.07

NS

15-HETE

ArA

2.03

1.96

0.16

NS

0.02

NS

NS

0.02

5,6-LXA4

ArA

0.13

0.16

0.03

NS

NS

NS

NS

NS

13(S)-HOTrE4

ALA

130.8

100.3

28.3

NS

0.08

0.08

NS

NS

17-HDoHE5

DHA

1.29

0.99

0.22

NS

<  0.01

NS

<  0.05

NS

RvD2

DHA

0.30

0.17

0.06

NS

NS

NS

NS

NS

  1. 1NS = P > 0.10; Cov = d 1 covariate values
  2. 2HETE Hydroxyeicosatetraenoic acid, LXA4 Lipoxin A4,HOTrE Hydroxyoctadecatrienoic acid, HDoHE Hydroxyl-docosahexaenoic acid, RvD2 Resolvin D2
  3. 3ArA Arachidonic acid, ALA α-Linolenic acid, DHA Docosahexaenoic acid
  4. 4Cov × cov: P = 0.08; cov × cov × trt: P = 0.08
  5. 5Cov × cov: P = 0.02; trt × lambs: P = 0.07
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Journal of Animal Science and Biotechnology

ISSN: 2049-1891