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Table 5 Lipoxygenase-derived oxylipids in plasma of control ewes and ewes treated with 90 mg meloxicam on d 1 and 4 after lambing (mean ± SEM; μmol/L)

From: Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes

 P-values1
Oxylipid2Substrate3CONMELSEMTrtCovCov × trtLambsHpcov × trt
5-HETEArA0.100.290.22NSNSNS0.07NS
15-HETEArA2.031.960.16NS0.02NSNS0.02
5,6-LXA4ArA0.130.160.03NSNSNSNSNS
13(S)-HOTrE4ALA130.8100.328.3NS0.080.08NSNS
17-HDoHE5DHA1.290.990.22NS<  0.01NS<  0.05NS
RvD2DHA0.300.170.06NSNSNSNSNS
  1. 1NS = P > 0.10; Cov = d 1 covariate values
  2. 2HETE Hydroxyeicosatetraenoic acid, LXA4 Lipoxin A4,HOTrE Hydroxyoctadecatrienoic acid, HDoHE Hydroxyl-docosahexaenoic acid, RvD2 Resolvin D2
  3. 3ArA Arachidonic acid, ALA α-Linolenic acid, DHA Docosahexaenoic acid
  4. 4Cov × cov: P = 0.08; cov × cov × trt: P = 0.08
  5. 5Cov × cov: P = 0.02; trt × lambs: P = 0.07