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Table 2 Effects of Api-PR19 and antibiotic on growing performance, immune organ index, and immune function of 21-day-old and 42-day-old broiler chickens

From: A novel apidaecin Api-PR19 synergizes with the gut microbial community to maintain intestinal health and promote growth performance of broilers

Item Period/age Indices CON AGP Api-PR19, mg/kg SEM P-value
100 200 300
Growth performance 1–21 d ADFI, g 54.49 54.28 54.72 54.72 54.13 0.439 0.992
ADG, g 39.09 39.74 39.99 40.57 39.85 0.325 0.735
FCR 1.394a 1.366ab 1.367ab 1.349b 1.359b 0.005 0.041
22–42 d ADFI, g 147.45 152.54 146.29 151.25 150.32 1.815 0.819
ADG, g 72.58 76.12 71.13 77.28 75.31 1.157 0.442
FCR 2.033 2.006 2.065 1.959 1.998 0.068 0.070
1–42 d ADFI, g 97.16 101.06 97.11 100.21 98.86 1.161 0.786
ADG, g 53.03 56.62 53.41 57.20 55.65 0.729 0.262
FCR 1.832a 1.783bc 1.820b 1.753c 1.775c 0.008 0.005
Immune organ development 21 d Thymus index 2.20 2.02 2.22 2.13 2.22 0.081 0.555
Spleen index 0.88 0.78 0.83 0.67 0.70 0.033 0.338
Bursa index 2.37a 1.60c 1.77b 1.72b 2.15a 0.772 0.025
42 d Thymus index 3.24 3.01 3.44 2.70 2.79 0.150 0.519
Spleen index 0.95 0.90 0.93 0.88 0.83 0.028 0.130
Bursa index 0.48 0.45 0.52 0.38 0.35 0.031 0.387
IgG 21 d Serum IgG 386.14 462.21 355.86 340.43 304.71 20.264 0.156
42 d Serum IgG 636.86 524.71 732.33 430.90 731.38 44.642 0.158
H5 & H9 antibody level (log2) 7 d H5 8.29 7.71 8.14 8.28 8.71 0.771 0.193
14 d 6.43 5.86 5.71 6.00 6.00 0.797 0.566
21 d 4.28 3.85 5.00 4.43 4.43 0.743 0.059
28 d 4.29 3.43 4.14 3.14 3.57 1.269 0.416
7 d H9 9.57a 8.00b 9.57a 9.43a 10.29a 1.374 0.024
14 d 7.29 6.86 6.71 6.43 6.43 1.121 0.612
21 d 4.43 4.00 4.14 4.43 4.57 0.900 0.775
28 d 3.57 3.71 2.86 3.29 4.00 1.091 0.363
  1. Note: ADFI average daily feed intake; ADG average daily weight gain; FCR ratio of feed intake to weight gain. a-b within a row with different superscripts means significantly difference