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Table 2 Effect of birth weight (n = 90), weaning treatment (n = 60) and days post-weaning (n = 36), and their interaction (n = 12-30), on oxidative stress biomarkers in weaned piglets

From: Changes of the glutathione redox system during the weaning transition in piglets, in relation to small intestinal morphology and barrier function

 

Birth weight (Biw)

Weaning treatment (WT)

Days post-weaning (DPW)

SEM

P-value

LBW

NBW

3d3w

3w

4w

d0

d2

d5

d12

d28

 

BiW

WT

DPW

BiW× DPW

WT× DPW

BiW× WT

ORAC, μmol trolox eq./mL

 PLA

23.4

23.5

22.6a

24.4b

23.3ab

24.1y

24.6z

24.2yz

22.7xy

21.7x

0.2

0.901

<0.001

<0.001

0.536

0.252

0.640

MDA, nmol/mg prot.

 PLA*

10.9

10.7

11.1

10.9

10.5

11.6z

11.0yz

10.2y

10.0y

11.3z

0.1

0.386

0.127

<0.001

0.713

0.661

0.306

 DUO

299

285

288

304

284

261y

283y

287yz

296yz

332z

6

0.210

0.337

<0.001

0.972

0.040

0.782

 JEJ

334

351

312a

371b

343ab

408z

416z

282y

296y

310y

8

0.301

0.016

<0.001

0.788

<0.001

0.402

 LIV

634

650

648

640

637

646y

504x

632y

675yz

754z

12

0.502

0.926

<0.001

0.825

0.005

0.343

  1. Birth weight (Biw), weaning treatment (WT), day post-weaning (DPW), oxygen radical scavenging activity (ORAC), malondialdehyde (MDA), blood plasma (PLA), duodenal mucosa (DUO), distal jejunal mucosa (JEJ), liver tissue (LIV). Piglets were either weaned at three weeks of age (3w), four weeks of age (4w), or separated from the sow at 3d of age and fed a milk replacer until weaning at 3w of age (3d3w), and either had a low birth weight or normal birth weight (NBW). a,b Within a row, means without a common superscript differ for the effect of weaning treatment (WT: P ≤ 0.05). x,y,z Within a row, means without a common superscript differ for the effect of days post-weaning (DPW: P ≤ 0.05). * Expressed in nmol/mL plasma