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Table 3 Quantitative trait loci (QTL) associated with milk traits recorded in Murciano-Granadina goats

From: Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats

QTL

Chromosome

Leading SNP

Position, Mb

#SNPs

MAF

Trait

β ± SE

P value

q-value

1

2

rs268253425

130.72-130.01

2

0.20

LP

−0.09 ± 0.02

1.50E-07

7.26E-03

2

3

rs268258472

113.47

1

0.38

LOL

−14.20 ± 3.21

1.04E-05

2.38E-02

3

6

rs268259784

4.40

1

0.35

PP

0.07 ± 0.02

8.21E-04

4.09E-02

4

6

rs268251267

15.64

1

0.24

PP

0.08 ± 0.03

7.85E-04

4.00E-02

5

6

rs268259390

56.51

1

0.02

DMP

1.08 ± 0.26

4.56E-05

3.56E-02

PP

0.29 ± 0.07

6.52E-05

8.48E-03

6

6

rs268290907

78.90-93.48

12

0.43

PP

−0.14 ± 0.02

3.19E-11

1.54E-06

6

rs268268356

84.67–86.86

2

0.40

DMP

−0.35 ± 0.08

1.14E-05

2.66E-02

6

rs268290907

86.86

1

0.43

FP

−0.18 ± 0.04

5.79E-06

1.36E-02

7

11

rs268250457

72.83

1

0.41

LOL

15.23 ± 3.30

4.40E-06

9.13E-03

8

12

rs268256521

68.10

1

0.12

LOL

−20.35 ± 4.76

2.07E-05

3.50E-02

9

13

rs268236131

53.62-54.38

2

0.32

SCC

0.22 ± 0.05

1.92E-05

3.05E-02

11

14

rs268255959

46.10

1

0.09

LP

−0.10 ± 0.02

2.56E-05

4.77E-02

10

14

rs268282962

56.92

1

0.01

FP

0.78 ± 0.18

1.78E-05

3.32E-02

12

15

rs268235117

34.69

1

0.06

MY210

−61.98 ± 13.53

4.95E-06

7.91E-03

13

15

rs268290053

35.51

1

0.07

FP

0.35 ± 0.08

4.82E-06

7.69E-03

14

15

rs268266747

63.95

1

0.23

SCC

0.23 ± 0.05

1.63E-05

2.60E-02

15

16

rs268236985

39.59

1

0.04

DMP

0.81 ± 0.20

6.39E-05

4.93E-02

16

16

rs268253363

47.67

1

0.21

DMP

0.42 ± 0.10

1.70E-05

2.62E-02

17

17

rs268238952

11.20

1

0.06

PP

0.22 ± 0.05

4.84E-06

2.13E-02

DMP

0.88 ± 0.17

3.89E-07

1.88E-02

18

18

rs268278435

29.64

1

0.04

DMP

0.84 ± 0.19

1.33E-05

1.70E-02

19

20

rs268277231

29.45

1

0.08

LP

−0.11 ± 0.03

3.35E-05

4.84E-02

20

22

rs268253724

25.30

1

0.36

FP

−0.18 ± 0.04

4.14E-05

4.68E-02

21

23

rs268243170

8.15

1

0.45

MY210

29.89 ± 6.76

1.03E-05

1.01E-02

22

24

rs268240589

49.71

1

0.32

LP

0.07 ± 0.02

9.51E-06

1.23E-02

23

28

rs268240830

23.02

1

0.42

LP

−0.06 ± 0.01

7.16E-05

1.66E-02

24

28

rs268246445

41.15-41.42

4

0.51

LP

−0.06 ± 0.01

3.21E-05

1.51E-02

  1. QTL Quantitative trait locus; Genome-wide significant associations are indicated in bold; leading SNP: a SNP showing the most significant association with a given trait, #SNPs number of SNPs, MAF minor allele frequency, PP protein percentage, FP fat percentage, LP lactose percentage, DMP dry matter percentage, SCC somatic cell count, LOL length of lactation, MY210 milk yield normalized to 210 d; β and SE denote the effect size of the marker (allele substitution effect) and its standard error, respectively