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Table 8 Effects of dietary supplementation with BLJ on gene expressions of proinflammatory cytokines, chemokines and TLR signaling pathway-related genes in the jejunums of broiler chickens challenged with NE (at 7 d after NE infection)

From: Dietary encapsulated essential oils and organic acids mixture improves gut health in broiler chickens challenged with necrotic enteritis

ItemsNE1TLR-2TLR-4MyD88TRAF-6NF-kBIFN-γTNFSF15IL-1βIL-8IL-10TollipPI3KA20SOCS-1SOCS-6
BLJ, mg/kg
 01.01ab1.661.021.02a1.061.011.00bc1.051.381.071.02ab1.041.101.061.02ab
 0+1.26ab0.881.010.96ac0.903.891.08b1.140.631.370.84b0.730.931.230.92b
 5001.45a0.591.111.13a1.161.131.32a1.020.750.811.16a1.261.351.071.45a
 500+0.91b0.460.870.36b0.393.130.79c0.621.021.240.57c0.731.701.190.67b
 SEM2 0.080.130.040.080.100.340.050.080.140.110.060.070.140.110.09
Main effect
 0 1.141.27a1.020.990.982.451.041.101.011.220.930.881.011.150.97
 500 1.180.52b0.990.740.782.131.060.820.891.020.861.001.531.131.06
 Non-challenged 1.231.13a1.071.071.11a1.07b1.161.041.070.941.091.15a1.221.071.23
 Challenged 1.090.67b0.940.660.64b3.51a0.930.880.831.300.700.73b1.321.210.80
P-value3
 BLJ 0.780< 0.010.7880.0180.2190.5000.8430.0850.6630.3600.3230.3240.0780.9570.561
 Challenged 0.3390.0170.118< 0.01< 0.01< 0.01< 0.010.3160.3810.107< 0.01< 0.010.7370.5250.013
 Challenged×BLJ 0.0130.0810.162< 0.010.0680.358< 0.010.1250.0730.775< 0.010.3190.3610.9140.044
  1. a, b, c Means within the same column with different superscripts differ significantly (P < 0.05)
  2. 1NE Co-challenged with Eimeria spp. and Clostridium perfringens; −, without NE challenge; +, with NE challenge
  3. 2SEM standard error of the mean
  4. 3P-values represent the main effect of the diet, the main effect of NE challenged, and the interaction between the dietary treatments and NE challenged