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Table 8 Effects of dietary supplementation with BLJ on gene expressions of proinflammatory cytokines, chemokines and TLR signaling pathway-related genes in the jejunums of broiler chickens challenged with NE (at 7 d after NE infection)

From: Dietary encapsulated essential oils and organic acids mixture improves gut health in broiler chickens challenged with necrotic enteritis

Items

NE1

TLR-2

TLR-4

MyD88

TRAF-6

NF-kB

IFN-γ

TNFSF15

IL-1β

IL-8

IL-10

Tollip

PI3K

A20

SOCS-1

SOCS-6

BLJ, mg/kg

 0

1.01ab

1.66

1.02

1.02a

1.06

1.01

1.00bc

1.05

1.38

1.07

1.02ab

1.04

1.10

1.06

1.02ab

 0

+

1.26ab

0.88

1.01

0.96ac

0.90

3.89

1.08b

1.14

0.63

1.37

0.84b

0.73

0.93

1.23

0.92b

 500

1.45a

0.59

1.11

1.13a

1.16

1.13

1.32a

1.02

0.75

0.81

1.16a

1.26

1.35

1.07

1.45a

 500

+

0.91b

0.46

0.87

0.36b

0.39

3.13

0.79c

0.62

1.02

1.24

0.57c

0.73

1.70

1.19

0.67b

 SEM2

 

0.08

0.13

0.04

0.08

0.10

0.34

0.05

0.08

0.14

0.11

0.06

0.07

0.14

0.11

0.09

Main effect

 0

 

1.14

1.27a

1.02

0.99

0.98

2.45

1.04

1.10

1.01

1.22

0.93

0.88

1.01

1.15

0.97

 500

 

1.18

0.52b

0.99

0.74

0.78

2.13

1.06

0.82

0.89

1.02

0.86

1.00

1.53

1.13

1.06

 Non-challenged

 

1.23

1.13a

1.07

1.07

1.11a

1.07b

1.16

1.04

1.07

0.94

1.09

1.15a

1.22

1.07

1.23

 Challenged

 

1.09

0.67b

0.94

0.66

0.64b

3.51a

0.93

0.88

0.83

1.30

0.70

0.73b

1.32

1.21

0.80

P-value3

 BLJ

 

0.780

< 0.01

0.788

0.018

0.219

0.500

0.843

0.085

0.663

0.360

0.323

0.324

0.078

0.957

0.561

 Challenged

 

0.339

0.017

0.118

< 0.01

< 0.01

< 0.01

< 0.01

0.316

0.381

0.107

< 0.01

< 0.01

0.737

0.525

0.013

 Challenged×BLJ

 

0.013

0.081

0.162

< 0.01

0.068

0.358

< 0.01

0.125

0.073

0.775

< 0.01

0.319

0.361

0.914

0.044

  1. a, b, c Means within the same column with different superscripts differ significantly (P < 0.05)
  2. 1NE Co-challenged with Eimeria spp. and Clostridium perfringens; −, without NE challenge; +, with NE challenge
  3. 2SEM standard error of the mean
  4. 3P-values represent the main effect of the diet, the main effect of NE challenged, and the interaction between the dietary treatments and NE challenged