Item | DIM2 | SEM | ST2 | SEM | P-value | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | −10 | −3 | 3 | 17 |  | −0.5 | 0.5 | 1.5 | 2.5 | 3.5 | 4.5 | 5.5 | 6.5 |  | DIM | ST | ST×DIM |
Portal flows, L/h | |||||||||||||||||
 Plasma | 164b | 164b | 167b | 274a | 7 | 189b | 205a | 208a | 201ab | 195ab | 188b | 187b | 168c | 7 | < 0.001 | < 0.001 | 0.46 |
 Blood | 227b | 228b | 229b | 375a | 9 | 262c | 294a | 282ab | 273bc | 265bc | 256c | 254c | 230d | 10 | < 0.001 | < 0.001 | 0.71 |
Net portal fluxes | |||||||||||||||||
 O2, mmol/h | − 457b | − 441b | − 411b | − 718a | 22 | − 479 | − 522 | − 555 | − 546 | − 506 | − 503 | − 492 | − 451 | 26 | < 0.001 | 0.07 | 0.06 |
 CO2, mmol/h | 560b | 534b | 503b | 936a | 28 | 639ab | 701a | 685ab | 658ab | 599b | 652ab | 619ab | 509c | 36 | < 0.001 | 0.007 | 0.07 |
 Insulin, mol/h | 23.5b | 17.9b | 32.3a | 35.7a | 2.7 | 15.6de | 70.8a | 28.5bc | 32.9b | 22.9cd | 20.6cd | 16.3de | 10.9e | 3.4 | < 0.001 | < 0.001 | 0.002 |
 Urea, mmol/h | −5.0b | (−2.6b) | −6.2b | −21.1a | 1.8 | (−4.0) | −11.2 | −9.9 | −7.7 | −8.7 | −6.9 | −10.6 | −10.6 | 2.6 | < 0.001 | 0.72 | 0.01 |
Essential AA, g/d | |||||||||||||||||
 Lys | 19.5b | 19.3b | 15.5c | 34.7a | 1.4 | 13.1d | 25.4b | 29.7a | 31.3a | 25.0b | 22.0b | 18.4c | 12.8d | 1.6 | < 0.001 | < 0.001 | 0.02 |
 Met | 4.2b | 3.8b | 3.7b | 8.0a | 0.6 | 1.5c | 7.2a | 7.1a | 6.8a | 5.7ab | 4.6b | 4.3b | 2.1c | 0.6 | < 0.001 | < 0.001 | 0.95 |
 Thr | 11.8b | 11.8b | 8.0c | 21.3a | 0.9 | 7.2e | 15.2bc | 17.7ab | 18.9a | 15.7b | 12.7cd | 10.8d | 7.5e | 1.1 | < 0.001 | < 0.001 | 0.10 |
 Trp | 4.8b | 4.7b | 3.9b | 8.9a | 0.4 | 2.5d | 6.0bc | 7.6a | 7.5a | 6.8ab | 5.9bc | 5.0c | 3.1d | 0.5 | < 0.001 | < 0.001 | 0.22 |
 Ile | 17.0b | 16.1b | 13.1c | 30.9a | 1.1 | 10.5d | 20.0bc | 26.2a | 27.0a | 21.3b | 20.1bc | 17.0c | 12.2d | 1.4 | < 0.001 | < 0.001 | 0.25 |
 Leu | 29.5b | 28.2b | 22.6c | 52.1a | 1.7 | 16.8d | 38.2b | 44.3a | 45.5a | 36.8b | 33.6bc | 29.3c | 20.6d | 2.1 | < 0.001 | < 0.001 | 0.008 |
 Val | 19.1b | 19.5b | 14.5c | 34.4a | 1.5 | 13.0d | 21.9bc | 28.7a | 30.5a | 26.2ab | 22.2bc | 18.3c | 14.2cd | 1.8 | < 0.001 | < 0.001 | 0.25 |
 His | 8.9b | 7.6b | 5.1c | 16.0a | 0.9 | 5.8cd | 11.6b | 12.2ab | 14.8a | 12.9ab | 7.9c | 4.4d | 5.7cd | 1.0 | < 0.001 | < 0.001 | 0.01 |
 Phe | 21.6b | 20.8b | 15.9c | 38.7a | 1.2 | 13.2e | 27.4bc | 31.9a | 32.1a | 28.9ab | 24.2cd | 21.8d | 14.6e | 1.5 | < 0.001 | < 0.001 | 0.003 |
Non-essential AA, g/d | |||||||||||||||||
 Ala | 50.8b | 44.9b | 37.3c | 93.0a | 2.7 | 35.7e | 66.7ab | 73.9a | 71.1ab | 59.9bc | 57.2cd | 49.4d | 38.0e | 3.3 | < 0.001 | < 0.001 | 0.02 |
 Asn | 9.8b | 8.7b | 5.5c | 14.7a | 0.6 | 4.4e | 9.7c | 14.2a | 14.1a | 11.7b | 9.8c | 7.8d | 5.7e | 0.7 | < 0.001 | < 0.001 | 0.003 |
 Asp | 8.8b | 8.7b | 8.5b | 14.0a | 0.6 | 6.0d | 11.0b | 12.8a | 13.6a | 11.0b | 10.6b | 8.3c | 6.6d | 0.7 | < 0.001 | < 0.001 | 0.009 |
 Cys | 5.4b | 5.9b | 2.7c | 9.0a | 0.6 | 4.4cd | 5.2bc | 6.6ab | 8.6a | 5.7bc | 7.1ab | 5.9b | 2.7d | 0.8 | < 0.001 | < 0.001 | 0.18 |
 Glu | −5.3a | −4.5a | −4.2a | (−0.6b) | 1.0 | −7.6a | −4.1b | −2.8b | (−2.2bc) | (0.5c) | −3.9b | − 3.9b | −5.3ab | 1.2 | 0.003 | < 0.001 | 0.75 |
 Gly | 34.6b | 32.6b | 30.9b | 63.5a | 2.3 | 38.6bcd | 37.0cd | 42.4abc | 43.4ab | 40.1abcd | 44.9a | 41.9abc | 34.8d | 2.7 | < 0.001 | 0.01 | 0.42 |
 Pro | 34.2b | 32.0b | 24.0c | 64.6a | 2.7 | 20.3e | 42.3b | 52.9a | 51.6a | 42.5b | 41.0bc | 33.6c | 25.3d | 3.2 | < 0.001 | < 0.001 | 0.006 |
 Ser | 19.1b | 18.1b | 13.8c | 34.0a | 1.2 | 10.6d | 24.3b | 27.8a | 29.3a | 24.6ab | 21.9b | 18.2c | 13.1d | 1.4 | < 0.001 | < 0.001 | 0.15 |
 Tyr | 15.5b | 14.7b | 11.3c | 27.2a | 0.9 | 8.3d | 20.0b | 22.8a | 23.7a | 20.1b | 17.9b | 14.4c | 10.1d | 1.0 | < 0.001 | < 0.001 | 0.01 |
 Gln | 12.4a | 12.2a | (4.6b) | 17.2a | 2.9 | (1.1c) | 12.2b | 21.7a | 18.2ab | 14.9ab | 15.6ab | 7.5c | (1.4) | 3.7 | 0.03 | < 0.001 | 0.85 |