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Table 1 microRNAs detected by edgeR as differentially expressed when comparing AL-T0 (fasted) gilts with their AL-T1 (5 h after eating) and AL-T2 (7 h after eating) counterparts

From: Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply

Contrast

miRNA

log2FCb

P-value

q-valuec

log2CPM AL-T0d

log2CPM AL-T1d

log2CPM AL-T2d

AL-T0/AL-T1a

ssc-miR-7-5p

0.9978

7.56E-05

2.16E-02

6.8416

7.5115

–

ssc-miR-374a-3p

0.8568

4.73E-04

3.81E-02

6.9201

7.5034

–

ssc-miR-7

0.9229

5.26E-04

3.81E-02

6.4206

7.0178

–

ssc-miR-148a-3p

0.8989

5.97E-04

3.81E-02

13.8692

14.5105

–

ssc-miR-1

0.7686

6.66E-04

3.81E-02

16.8124

17.3183

–

ssc-miR-32

1.2420

9.92E-04

4.73E-02

2.9824

3.6098

–

AL-T0/AL-T2a

ssc-miR-1285

−2.9830

3.47E-09

9.92E-07

7.9799

–

5.5849

ssc-miR-148a-3p

1.3831

2.39E-06

2.83E-04

13.8692

–

14.9315

ssc-miR-7-5p

1.1592

2.97E-06

2.83E-04

6.8416

–

7.6948

ssc-miR-493-5p

0.7464

3.84E-05

2.37E-03

6.4846

–

7.1191

ssc-miR-7

1.0724

4.14E-05

2.37E-03

6.4206

–

7.1910

ssc-miR-22-3p

−0.9814

1.01E-04

4.20E-03

12.6857

–

11.7583

ssc-miR-421-5p

1.2893

1.03E-04

4.20E-03

2.6775

–

3.7359

ssc-miR-758

−0.7536

1.24E-04

4.43E-03

5.4106

–

4.5480

ssc-miR-339

−0.8760

1.68E-04

5.34E-03

2.8919

–

2.0274

ssc-let-7f-1

0.7735

2.36E-04

6.43E-03

14.0981

–

14.7031

ssc-let-7f-5p

0.7641

2.74E-04

6.43E-03

12.4788

–

13.0761

ssc-miR-374a-3p

0.9025

2.75E-04

6.43E-03

6.9201

–

7.5867

ssc-miR-30a-3p

0.6600

3.36E-04

6.43E-03

9.8397

–

10.3833

ssc-miR-151-3p

0.6940

3.37E-04

6.43E-03

12.3832

–

12.9732

ssc-miR-129a-3p

−1.3858

4.09E-04

7.05E-03

4.7123

–

3.0830

ssc-miR-296-5p

−0.9342

4.79E-04

7.61E-03

5.1094

–

3.9239

ssc-miR-30e-3p

0.6430

7.45E-04

1.12E-02

10.8497

–

11.3840

ssc-miR-98

0.7127

1.24E-03

1.69E-02

9.6818

–

10.2075

ssc-let-7a-1

0.4660

1.13E-03

2.53E-02

13.7761

–

14.1002

ssc-let-7a-2

0.4590

1.43E-03

2.53E-02

12.4875

–

12.8046

ssc-miR-503

0.4912

1.12E-03

2.53E-02

7.8380

–

8.1776

ssc-miR-181c

−0.6665

2.02E-03

2.56E-02

3.0770

–

2.3722

ssc-miR-32

1.1189

2.11E-03

2.56E-02

2.9824

–

3.5525

ssc-miR-1

0.6586

2.15E-03

2.56E-02

16.8124

–

17.2479

ssc-miR-450b-3p

0.9689

2.78E-03

2.95E-02

1.3512

–

2.0993

ssc-miR-136-5p

0.9319

2.78E-03

2.95E-02

3.4211

–

3.8968

ssc-miR-7857-3p

−1.1003

3.03E-03

3.09E-02

2.3255

–

1.5283

ssc-miR-125b

−0.5858

1.88E-03

3.20E-02

13.0432

–

12.3566

ssc-miR-361-5p

−0.5109

3.02E-03

4.45E-02

7.4597

–

6.8061

ssc-miR-362

−0.5567

3.45E-03

4.61E-02

6.5327

–

5.8194

ssc-miR-218b

0.7746

4.75E-03

4.62E-02

4.8429

–

5.2796

ssc-miR-532-3p

−0.6865

4.84E-03

4.62E-02

7.4422

–

6.5930

ssc-miR-365-3p

−0.7367

5.36E-03

4.79E-02

9.9681

–

8.9921

  1. aAL-T0: Duroc gilts in a fasting condition (N = 11); AL-T1: Duroc gilts slaughtered after 5 h of food intake (N = 12); AL-T2: Duroc gilts slaughtered after 7 h of food intake (N = 12)
  2. bLog2FC: estimated log2 fold change mean expression levels
  3. cq-value: P-value corrected for multiple testing with the Benjamini-Hochberg procedure
  4. dLog2CPM: estimated log2 counts-per-million (CPM) mean expression levels in AL-T0, AL-T1 and AL-T2 groups
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Journal of Animal Science and Biotechnology

ISSN: 2049-1891