Fig. 6

Network of up-regulators (center in the network) with the highest impact in controlling the difference in the adipose tissue transcriptome from dairy cows fed a control diet (CTR) or a higher-energy diet prepartum (OVR) at − 14 d relative to parturition. Orange shades denote activation and blue shades inhibition of the up-regulators. Red shades denote up-regulation while green shades denote down-regulation. Blue and orange dotted lines in arrows denote the inhibition and activation effect, respectively, of the up-stream regulators on target genes