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Fig. 4 | Journal of Animal Science and Biotechnology

Fig. 4

From: The proteome of IVF-induced aberrant embryo-maternal crosstalk by implantation stage in ewes

Fig. 4

Disrupted protein homeostasis and impaired ECM interaction in IVF endometrial IC areas. a Classification of GO terms based on functional annotation of ‘biological process’, ‘cellular component’, and ‘molecular function’, using DEPs between the IVO and IVF IC areas. The left ordinate represents the number of DEPs enriched in each term [defined as log2 (No. of enriched genes)], and the right ordinate represents the enrichment score [defined as –log10(P-value)]. b Heat map of DEPs associated with ribosome, translation, and proteasome in the IVO and IVF IC areas. Z-score normalized protein abundance is represented in red (relatively high) and green (relatively low). c Comparisons of the total abundance of 1611 proteins of the IVO and IVF C area samples. Each circle indicates the total abundance of 1611 proteins in a biological replicate from the IVO or IVF IC area samples. d Quantitation of total protein concentration per gram of tissue in IVO and IVF C area samples. Data represent the mean ± SEM of three independent biology replicates, *P < 0.05. e Normalized abundance of proteins encoded by interferon-induced genes in the IVO and IVF IC area samples. Data represent the mean ± SEM, * P < 0.05. f Heat map of DEPs associated with the cell cycle and ECM receptor in the IVO and IVF IC areas. Z-score normalized protein abundance is represented in red (relatively high) and green (relatively low)

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