Table 2 Differentially expressed genes with a P-value < 0.01 and fold change ≤ − 4 in liver tissue harvested 10 days prior to parturition from Holstein cows with (KET) or without (OVE) clinical ketosis during the first week postpartum. Both groups of cows were fed a diet containing 1.54 Mcal/kg of dry matter and 15.0% crude protein from − 21 days prepartum to calving, and a common lactation diet containing 1.75 Mcal/kg of dry matter and 17.5% crude protein
Symbol | Description | KET vs. OVE |
|---|---|---|
DOCK3 | Dedicator of cytokinesis 3 | −8.12 |
FAM131A | Family with sequence similarity 131, member A | −6.91 |
LOC528412 | Multidrug resistance-associated protein 4 | −6.80 |
COBRA1 | Cofactor of BRCA1 | −6.24 |
CPXM2 | Carboxypeptidase X (M14 family), member 2 | −6.13 |
UNC13D | Unc-13 homolog D (C. elegans) | −5.18 |
LOC780781 | Keratin associated protein | −5.11 |
BTBD10 | BTB (POZ) domain containing 10 | −5.09 |
BAD | BCL2-associated agonist of cell death | −5.08 |
NEU4 | Sialidase 4 | −5.08 |
SS18 | Synovial sarcoma translocation, chromosome 18 | −4.82 |
TAPBPL | TAP binding protein-like | −4.80 |
KIAA0922 | KIAA0922 ortholog | −4.77 |
APOBR | Apolipoprotein B receptor | −4.68 |
PROK2 | Prokineticin 2 | −4.64 |
WDR6 | WD repeat domain 6 | −4.60 |
EVC2 | Ellis van creveld syndrome 2 | −4.58 |
SYN3 | Synapsin III | −4.50 |
GLCCI1 | Glucocorticoid induced transcript 1 | −4.50 |
DLGAP5 | Discs, large (Drosophila) homolog-associated protein 5 | −4.47 |
CIB2 | Calcium and integrin binding family member 2 | −4.47 |
TBC1D19 | TBC1 domain family, member 19 | −4.41 |
ARNT | Aryl hydrocarbon receptor nuclear translocator | −4.40 |
ACPT | Acid phosphatase, testicular | −4.40 |
MAPK3 | Mitogen-activated protein kinase 3 | −4.39 |
TUBG1 | Tubulin, gamma 1 | −4.39 |
NCOA2 | Nuclear receptor coactivator 2 | −4.29 |
REN | Renin | −4.25 |
DST | Predicted: Dystonin, transcript variant 1 | −4.23 |
PTK2 | PTK2 protein tyrosine kinase 2 | −4.21 |
HCN1 | Hyperpolarization activated cyclic nucleotide-gated potassium channel 1 | −4.20 |
DEFB1 | Defensin, beta 1 | −4.16 |
TTF2 | Transcription termination factor, RNA polymerase II | −4.13 |
NPB | Neuropeptide B | −4.13 |
RAB27A | RAB27A, member RAS oncogene family | −4.09 |
ZYG11A | Zyg-11 homolog A (C. elegans) | −4.08 |
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4 | −4.06 |
TPGS1 | Predicted: Chromosome 7 open reading frame, human C19orf20 | −4.04 |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 | −4.00 |