Table 1 Differentially expressed genes with a P-value < 0.01 and fold change ≥3 in liver tissue harvested 10 days prior to parturition from Holstein cows with (KET) or without (OVE) clinical ketosis during the first week postpartum. Both groups of cows were fed a diet containing 1.54 Mcal/kg of dry matter and 15.0% crude protein from − 21 days prepartum to calving, and a common lactation diet containing 1.75 Mcal/kg of dry matter and 17.5% crude protein
Symbol | Description | KET vs. OVE |
|---|---|---|
CCL2 | Chemokine (C-C motif) ligand 2 (CCL2) | 5.12 |
CLCA2 | Chloride channel accessory 2 | 5.09 |
CACNA1D | Calcium channel, voltage-dependent | 4.51 |
ADARB2 | Adenosine deaminase, RNA-specific | 4.51 |
KRT9 | Keratin 9 | 4.45 |
KIFC2 | Kinesin family member C2 | 4.34 |
MARK1 | MAP/microtubule affinity-regulating kinase 1 | 4.22 |
POLE2 | Polymerase (DNA directed), epsilon 2 (p59 subunit) | 4.19 |
SLC22A2 | Solute carrier family 22 (organic cation transporter), member 2 | 4.06 |
GPR63 | G protein-coupled receptor 63 | 3.98 |
ANO3 | Anoctamin 3 | 3.88 |
XK | X-linked Kx blood group (McLeod syndrome) | 3.83 |
DUSP4 | Dual specificity phosphatase 4 | 3.73 |
SPATA7 | Spermatogenesis associated 7 | 3.64 |
ZC3H4 | Zinc finger CCCH-type containing 4 | 3.59 |
SYCE3 | Synaptonemal complex central element protein 3 | 3.57 |
MYRIP | Myosin VIIA and Rab interacting protein | 3.40 |
LOC787081 | Predicted: UPF0632 protein A | 3.36 |
CNR1 | Cannabinoid receptor 1 (brain) | 3.21 |
SPATA17 | Predicted: spermatogenesis associated 17 | 3.20 |
PCBP3 | Poly(rC) binding protein 3 (PCBP3) | 3.09 |
ADAM32 | ADAM metallopeptidase domain 32 (ADAM32) | 3.08 |